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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1968




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Hormone Contraception: Studies of Adrenal Function.



AUTHORS

Gold EM


SOURCE

In: Hoffman, F., ED. Advanced concepts in contraception (Proceedings of Four

Symposia, Los Angeles, Philadelphia, New York, Boston). New York, Excerpta

Medica Foundation, 1968



ABSTRACT

Our studies confirmed earlier findings by others that in one commonly used test, the SU-4885 test, pituitary ACTH

reserve was suppressed in women who underwent two or more years of cyclic therapy with contraceptive steroids. On

cessation of treatment, a normal response returned. Our data indicate that the progestogen component, ethynodiol

diacetate, when given alone, had no effect on the SU-4885 test, and that the estrogen, ethinyl estradiol, was primarily

responsible for test inhibition. Other indices, such as resting steroid output and response to exogenous ACTH,

were little influenced by therapy; however, a statistically significant reduction in resting urinary 17-ketogenic steroids

was found during treatment. Although the abnormality in SU-4885 response remains to be elucidated, it was

demonstrated in these cases to be associated with a rise in transcortin as well as with a significant reduction in

"cortisol glucuronide conjugate" concentrations (following ACTH), a finding not previously appreciated. The latter

impairment, at least theoretically, could lead to suppression of ACTH release by prolonging the circulatory life of

endogenous cortisol, but it remains to be shown by tests other than the SU-4885 procedure that pituitary-adrenal

impairment does in fact exsist. Studies along this line, employing hypoglycemia as a challenge, are in progress.

(PubHealth.info Document ID: CONT9T 1083-06)



PubHealth.info NOTE: The author(s) of this article titled, "Hormone Contraception: Studies of Adrenal Function.",

is(are) Gold EM. The source of this article is "In: Hoffman, F., ED. Advanced concepts in contraception (Proceedings

of Four Symposia, Los Angeles, Philadelphia, New York, Boston). New York, Excerpta Medica Foundation, 1968".

This article was published in 1968 in English language(s). (PubHealth.info® Document ID: CONT9T 1083-06. All

rights reserved with PubHealth.info) PIN: 41083





 

 

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