Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1968

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Hormone contraception: liver function and other biochemical studies.

AUTHORS

Allan JS

SOURCE

In: Hoffman, F., ed. Advanced concepts in contraception: (Proceedings of four

symposia, Los Angeles, Philadelphia, New York, Boston.) New York, Excerpta

Medica Foundation, 1968. p.14-15

ABSTRACT

Of a number of biochemical tests performed on a large number of patients, both before and after taking hormonal

contraceptives, only the liver function tests showed abnormal results. 2.3% of control patients had abnormal

standard sulfobromophthalein tests. Of 711 patients treated with hormonal contraceptives 6.8% showed abnormal

retention of the dye. Subsequent tests on those showing dye retention were normal. These patients were free of

clinical evidence of liver disease. It was noted that the dose of sulfobromophthalein had been based on the weight

of the patient and those showing retention were mostly obese. It has been shown by others that excessive steroids

in the blood interfere with the function of the liver to remove the dye. The majority of abnormal tests had occurred

during the latter part of the menstrual cycle and extended into menstruation. Patients who had taken 10 mg of

Norethisterone for 5 years had a 20% incidence of abnormal tests. After 3 more years of the same therapy the results

were the same. Reducing the dose to 1 mg diminished the percentage of abnormal dye retention tests gradually to

5% in 6 months. Therefore true liver damage was not considered present. It can be predicted that obese patients

are the ones most likely to have abnormal sulfobromophthalein retention tests during the luteal period of the cycle

when increased steroids are normally present in the blood stream. After the early phases of hormonal treatment

some kind of adaptation phenomenon may occur. (PubHealth.info Document ID: CONT9T 1081-06)

PubHealth.info NOTE: The author(s) of this article titled, "Hormone contraception: liver function and other

biochemical studies.", is(are) Allan JS. The source of this article is "In: Hoffman, F., ed. Advanced concepts in

contraception: (Proceedings of four symposia, Los Angeles, Philadelphia, New York, Boston.) New York, Excerpta

Medica Foundation, 1968. p.14-15". This article was published in 1968 in English language(s). (PubHealth.info®

Document ID: CONT9T 1081-06. All rights reserved with PubHealth.info) PIN: 41081

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