Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1968

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Evaluation of ORF-1658, a new formulation for sequential oral contraceptive

therapy.

AUTHORS

Rovinsky JJ

SOURCE

Fertility and Sterility 19(3): 390-404. 1968.

ABSTRACT

The effectiveness and safety of a new sequential oral contraceptive formulation was evaluated. The subjects

received 14 80 mcg tablets of mestranol followed by 6 tablets of 2 mg 3-desoxyacetoxymethyl progesterone (ORF-

1658) plus mestranol. The overall pregnancy rate was .25 + or - .24/100 woman-years of exposure. The

discontinuation rate for drug-related reasons was 2.5%. Amenorrhea (6.3%), headache (5.2%), and dizziness (3.4%)

were the most commonly reported side effects. This sequential therapy is recommended over the combined therapy

regimen because of a lower incidence of irregular bleeding, premenstrual tension syndrome, and increased weight

gain. However, in cases of menorrhagia or dysmenorrhea, the combined therapy is recommended. (PubHealth.info

Document ID: CONT9T 1018-06)

PubHealth.info NOTE: The author(s) of this article titled, "Evaluation of ORF-1658, a new formulation for sequential

oral contraceptive therapy.", is(are) Rovinsky JJ. The source of this article is "Fertility and Sterility 19(3): 390-404.

1968.". This article was published in 1968 in English language(s). (PubHealth.info® Document ID: CONT9T 1018-

06. All rights reserved with PubHealth.info) PIN: 41018

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