Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1968

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effects of low-dose oral contraceptives on blood coagulation.

AUTHORS

Poller L; Tabiowo A; Thompson JM

SOURCE

British Medical Journal 3: 218-219. July 27, 1968.

ABSTRACT

These investigations were designed to determine whether the increase in plasma clotting factors 7 and 10 in women

taking oral contraceptive preparations depended on the dose of the antiovulatory agent and whether the time

relationship of the changes would be affected by the hormonal dose. Participants were 31 patients on Ortho-novin

who had not preciously taken oral contraceptives and 60 women on Norinyl-1. Of those on Norinyl-1, 34 had not

previously taken oral contraceptives and 26 had been taking some other preparation within the preceding 6 months.

Ortho-novin (norethisterone 2 mg, mestranol .1 mg) contains twice the amount of hormones as norinyl-1. Both are

low-dose oral contraceptives. A control group consisted of normal females in the third trimester of pregnancy.

Another control group of equal numbers of normal females was compared. Prothrombin activity (quick's test),

cephalin time and factors 7 and 10 assays were done. Clotting factors were studied before starting the pill

preparation. During treatment they were tested at 6 week intervals for 3 months and then at 3 months intervals for 9

months. No significant difference in the prothrombin tests was found between any of the groups. Cephalin times

showed a shortening from the sixth months onward for the combined groups of all contraceptors. Factors 7 and 10

levels were increased in each of the 3 groups of patients on oral contraceptives from the third month onward. There

was no difference between the patients on Norinyl-1 and Ortho-novin. Therefore no dose relationship was shown.

Patients on Norinyl-1 who had taken other preparations previously showed a raised level of factor peristed and

continued to rise during the study. Results of factors 7 and 10 after the 9 months of treatment were less than those

of antinatal patients in their third trimester of pregnancy. (PubHealth.info Document ID: CONT9T 1004-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effects of low-dose oral contraceptives on blood

coagulation.", is(are) Poller L; Tabiowo A; Thompson JM. The source of this article is "British Medical Journal 3:

218-219. July 27, 1968.". This article was published in 1968 in English language(s). (PubHealth.info® Document ID:

CONT9T 1004-06. All rights reserved with PubHealth.info) PIN: 41004

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