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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1968




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Effect of oral contraceptives on depressive mood changes and on endometrial

monoamine oxidase and phosphatases.



AUTHORS

Grant EC; Pryse-Davies J


SOURCE

British Medical Journal 3: 777-780. September 28, 1968.



ABSTRACT

This study tabulated the incidence of depression and loss of libido, as well as histochemical changes in

monoamine oxidase (high activity of this enzyme in the brain is associated with depression) and alkaline and acid

phosphatases (reference enzymes) in endometrial biopsies from 797 women using oral contraceptives. Highly

progestogenic formulations (ranked by incidence of breakthrough bleeding) evoked depression and loss of libido in

28% of patients taking ethinyl estradiol and 17% of those taking mestranol, compared with 5% of sequential users.

Premenstrual tension almost invariably improved. Endometrial monoamine oxidase rises dramatically in the late

secretory phase in untreated menstrual cycles. In these women, the enzyme reaction was strong from day 12 in

those taking highly progestogenic combined pills, variable from day 17 in those taking weakly progestogenic

combined pills, and low throughout the cycle in those taking sequential pills. (PubHealth.info Document ID:

CONT9T 1001-06)



PubHealth.info NOTE: The author(s) of this article titled, "Effect of oral contraceptives on depressive mood changes

and on endometrial monoamine oxidase and phosphatases.", is(are) Grant EC; Pryse-Davies J. The source of this

article is "British Medical Journal 3: 777-780. September 28, 1968.". This article was published in 1968 in English

language(s). (PubHealth.info® Document ID: CONT9T 1001-06. All rights reserved with PubHealth.info) PIN: 41001






 

 

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