Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1973

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effect of steroidal contraceptives on levels of plasma androgen sulphates

and cortisol.

AUTHORS

Bulbrook RD; Herian M; Tong D; Hayward JL; Swain MC; Wang DY

SOURCE

Lancet 1(7804): 628-631. March 1973.

ABSTRACT

To investigate the effects of steroid contraceptives on androgen production, 123 women (ages 29-47) using steroid

contraceptives and 69 controls were studied. Blood (50 ml.) was taken between 2 and 10 P.M., plasma was

separated from the heparinised blood and stored at -20 degrees until analysis. Plasma D.S. and A.S. concentrations

were determined by the Wang method. Plasma-cortisol was measured by a competitive-binding technique. The

degree of binding to plasma proteins was determined by equilibrium dialysis. Mean cortisol levels were higher (10.0

mu-g vs. 6.4 mu-g/100 ml) in all oral contraceptive users; mean level of D.S. was significantly lower (100 vs. 130 mu-

g/100 ml); mean level of A.S. was also lower (27 vs. 42 mu-g/100 ml); the percentage of binding of cortisol to

plasma-proteins was significantly higher; the estimate of free cortisol concentration was the same for the two groups;

mean amounts of urinary androsterone and actiocholamolone excreted by contraceptive group was subnormal.

Changes in ketosteroid levels found in contraceptive group appear to resemble those found in women with a high risk

of breast cancer, suggesting steroidal contraceptives increase risk of breast cancer. (PubHealth.info Document ID:

CONT8T 588-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effect of steroidal contraceptives on levels of plasma

androgen sulphates and cortisol.", is(are) Bulbrook RD; Herian M; Tong D; Hayward JL; Swain MC; Wang DY.

The source of this article is "Lancet 1(7804): 628-631. March 1973.". This article was published in 1973 in English

language(s). (PubHealth.info® Document ID: CONT8T 588-06. All rights reserved with PubHealth.info) PIN: 35588

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