Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1973

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effect of oral contraceptive therapy on the renin-angiotensin system in

normotensive and hypertensive women.

AUTHORS

Tapia HR; Johnson CE; Strong CG

SOURCE

Obstetrics and Gynecology 41(5): 643-649. May 1973.

ABSTRACT

Plasma renin activity, plasma renin substrate (angiotensinogen), angiotensin I (AI), and plasma angiotensinase

activity were measured in 8 women who had first become hypertensive during a mean 3.1 years on various oral

contraceptives, and in 5 normotensive women, before and after 1 cycle of pills. All were determined by

radioimmunoassay. 8 or more blood pressures were taken by 2 observers and averaged. Plasma renin activity

increased from mean 2.12 to 3.52 ng/ml/hr (p greater than .2) in normal women, and from 3.0 to 5.06 in hypertensives

(p less than .02). The mean plasma renin substrate values for both groups together rose from 1881 ng/ml to 4245

ng/ml. Angiotensin I rose from .029 ng/ml/hr to .049 in normals, and .027 to .037 in hypertensives. Mean plasma

angiotensinase activity values rose from 3.6 to 5.4% degraded per minute in normal women and varied only from 6.5

before and to 5.9 after a pill cycle in hypertensive patients. The authors suggest that development of hypertension

during oral contraceptive therapy may be due to abnormal inactivation of angiotensin. (PubHealth.info Document ID:

CONT8T 572-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effect of oral contraceptive therapy on the renin-angiotensin

system in normotensive and hypertensive women.", is(are) Tapia HR; Johnson CE; Strong CG. The source of this

article is "Obstetrics and Gynecology 41(5): 643-649. May 1973.". This article was published in 1973 in English

language(s). (PubHealth.info® Document ID: CONT8T 572-06. All rights reserved with PubHealth.info) PIN: 35572

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