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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1973




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Effect of oral contraceptive on urinary metabolite excretions after

administration of L-tryptophan or L-kynurenine sulfate.



AUTHORS

Leklem JE; Rose DP; Brown RR


SOURCE

Metabolism; Clinical and Experimental 22(12): 1499-1505. 1973.



ABSTRACT

The metabolism of orally administered L-tryptophan and L-kynurenine was altered in 18 women who were using oral

contraceptives when compared with 12 who were not. Without prior loading of the system with L-tryptophan and L-

kynurenine acid, normal levels of metabolite in the tryptophan nicotinic acid ribonucleotide pathway were collected in

the urine. After amine acid ingestion, excretion of kynurenine, acetylkynurenine, 3-hydroxykynurenine, 3-

hydroxyanthranilic acid, and xanthurenic acid was elevated. The presence of progestogen may alter the effect of

estrogen on tryptophan metabolism. The elevations in the ratio of 3-hydroxykynurenine to 3-hydroxyanthranilic acid

suggested an impairment of kynureninase activity. (PubHealth.info Document ID: CONT8T 570-06)



PubHealth.info NOTE: The author(s) of this article titled, "Effect of oral contraceptive on urinary metabolite excretions

after administration of L-tryptophan or L-kynurenine sulfate.", is(are) Leklem JE; Rose DP; Brown RR. The source

of this article is "Metabolism; Clinical and Experimental 22(12): 1499-1505. 1973.". This article was published in

1973 in English language(s). (PubHealth.info® Document ID: CONT8T 570-06. All rights reserved with

PubHealth.info) PIN: 35570





 

 

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