Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1973

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effect of an oral contraceptive on NaCl appetite and preference threshold in

rats.

AUTHORS

Fregly MJ

SOURCE

Pharmacology, Biochemistry, and Behavior 1(1): 61-65. January-February 1973.

ABSTRACT

A study was undertaken to determine whether administration of the oral contraceptive Enovid to 10 male Long Evans

hooded rats was accompanied by a reduction in the preference threshold for a sodium chloride (NaCl) solution.

Dietary administration of Enovid at 7.5 mg/kg of food for 25 days was accompanied by a spontaneous appetite for salt

solution when the rats were given a choice between distilled water and a .15 M NaCl solution to drink.

Administration of the progestational component of Enovid, norethynodrel, at 7.5 and 15.0 mg/kg of food for 2 weeks

induced a spontaneous NaCl appetite in other male rats. The estrogenic compound, ethynyl estradiol, administered

in food at 1.0 and 2.0 mg/kg for 2 weeks, was also accompanied by an appetite for NaCl solution in male rats. Thus,

the NaCl appetite induced by Enovid may be associated with both its estrogenic and progestational components.

Other studies have been conducted to determine the effect of chronic administration of Enovid at 7.5 mg/kg of food

on the preference (detection) threshold of female rats for NaCl solution. Drug treatment was accompanied by a

significant reduction in preference threshold (.015 M) compared to controls (.030 M). The volume of NaCl solution

ingested by treated rats was greater than that of control rats at all concentrations tested above threshold, including

hypertonic concentrations. The results suggest that Enovid induces an appetite for NaCl solution and reduces the

preference threshold for this salt. (PubHealth.info Document ID: CONT8T 564-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effect of an oral contraceptive on NaCl appetite and

preference threshold in rats.", is(are) Fregly MJ. The source of this article is "Pharmacology, Biochemistry, and

Behavior 1(1): 61-65. January-February 1973.". This article was published in 1973 in English language(s).

(PubHealth.info® Document ID: CONT8T 564-06. All rights reserved with PubHealth.info) PIN: 35564

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