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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1973




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Diethylstilbestrol as a "morning-after" contraceptive.



AUTHORS


SOURCE

Medical Letter on Drugs and Therapeutics 15(14): 58-59. July 6, 1973.



ABSTRACT

Diethylstilbestrol (DES) is a nonsteroidal synthetic estrogen. It has been approved as a "morning-after" contraceptive.

It is thought to interfere with the implantation of the fertilized ovum. Among 5593 women treated with DES or other

estrogens, 26 pregnancies have been reported. Most of these patients reported midcycle exposures. Of 92 patients

with adenocarcinoma of the vagina or cervix, prenatal histories of 66 were obtained. The mothers of 49 of them had

taken DES or related nonsteroidal estrogens during pregnancy. In 1 case the mother had received only 1.5 mg daily.

Another mother was treated for only 5 days during the first trimester. There is no evidence that the use of DES

increases the risk of cancer in the mother. The Food and Drug Administration has approved the use of DES as an

emergency treatment only. Early therapeutic abortion is recommended when this use of DES fails, because of the

possibility of a teratogenic effect. The recommended oral dosage is 25 mg twice daily for 5 consecutive days, begun

within 72 hours after sexual exposure. Severe nausea and vomiting may occur. Headaches and menstrual

irregularities have also been reported. (PubHealth.info Document ID: CONT8T 536-06)



PubHealth.info NOTE: The author(s) of this article titled, "Diethylstilbestrol as a "morning-after" contraceptive.",

is(are) . The source of this article is "Medical Letter on Drugs and Therapeutics 15(14): 58-59. July 6, 1973.". This

article was published in 1973 in English language(s). (PubHealth.info® Document ID: CONT8T 536-06. All rights

reserved with PubHealth.info) PIN: 35536





 

 

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