Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1974

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Some metabolic actions and possible toxic effects of hormonal contraceptives

in animals and man. (Presented at the meeting on Pharmacological Models to

Assess Toxicity and Side Effects of Fertility Regulating Agents, Geneva,

September 17-20, 1973)

AUTHORS

Drill VA

SOURCE

Acta Endocrinologica 75(185): 169-202. 1974.

ABSTRACT

A review of certain effects of oral contraceptives is presented. The areas selected for comment include: 1)

endocrine effects, 2) side effects, 3) thromboembolic disease, 4) clotting factors and platelets, 5) breast lesions, and

6) metabolic effects related to thyroid and adrenal glands. There is a good correlation between the endocrine

effects of progestins and oral contraceptives in laboratory animals and their actions in women. The use of controls

is very important in studying side effects. From the data supplied by many studies, it is concluded that most of the

"side effects" commonly associated with the oral contraceptives are not reactions to the medication. It has not been

demonstrated that oral contraceptives cause thrombosis in animals or in women. During pregnancy and oral

contraceptive use, the blood level of clotting factors is increased but the incidence of thromboembolic disease is

not. The platelet count remains normal in pregnant rats, in human pregnancy, and in animals and women on oral

contraceptive therapy. Various studies conducted with oral contraceptives continue to demonstrate that the oral

contraceptives used clinically do not have any adverse effect with regard to breast cancer in women. A discussion of

metabolic effects limited to a review of data on oral contraceptives and adrenal and thyroid gland function and

changes in the protein binding of cortisol and thyroxine seems to indicate further that the action of drugs in

experimental animals can serve to predict effects which may be expected to occur in man. (PubHealth.info Document

ID: CONT7T 3545-06)

PubHealth.info NOTE: The author(s) of this article titled, "Some metabolic actions and possible toxic effects of

hormonal contraceptives in animals and man. (Presented at the meeting on Pharmacological Models to Assess

Toxicity and Side Effects of Fertility Regulating Agents, Geneva, September 17-20, 1973)", is(are) Drill VA. The

source of this article is "Acta Endocrinologica 75(185): 169-202. 1974.". This article was published in 1974 in

English language(s). (PubHealth.info® Document ID: CONT7T 3545-06. All rights reserved with PubHealth.info) PIN:

33545

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