Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1974

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Reversible contraceptive action of testosterone in males.

AUTHORS

Reddy PR

SOURCE

Journal of Reproduction and Fertility 38(1): 232. May 1974.

ABSTRACT

Seven healthy human volunteers were injected with 25 mg/day testosterone propionate for 60 days. Sperm counts

and volume of semen were recorded at 15-day intervals. The subjects were aspermic at the end of the treatment.

Following the withdrawal of treatment there was a gradual increase in the sperm counts reaching normal levels about

150 days later. During the period of testosterone treatment and recovery, the volume of semen did not show any

variation. Libido and potency of the volunteers was normal during the experimental period. This study suggests the

possibility of using testosterone as an antifertility agent in human males. However, since daily injection of the drug

is impractical as a method of contraception, subcutaneous silastic capsules filled with testosterone were used in

rats. The rats, bearing two silastic capsules of testosterone for 2 months, showed inhibition of spermatogenesis

and atrophic Leydig cells. Females mated with these experimental males but did not litter. Testicular histology and

fertility were restored to normal 1 month after removal of the capsules. This study suggests that low doses of

testosterone released through silastic capsules can be used for the control of fertility in male rats and it would be of

interest to investigate the applicability of this method in men. (PubHealth.info Document ID: CONT7T 3517-06)

PubHealth.info NOTE: The author(s) of this article titled, "Reversible contraceptive action of testosterone in males.",

is(are) Reddy PR. The source of this article is "Journal of Reproduction and Fertility 38(1): 232. May 1974.". This

article was published in 1974 in English language(s). (PubHealth.info® Document ID: CONT7T 3517-06. All rights

reserved with PubHealth.info) PIN: 33517

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