Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1974

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Radioimmunoassay of contraceptive steroids. 2. Synthesis of 6,7-tritiated-

mestranol and ethinylestradiol of high specific activity.

AUTHORS

Kundu N

SOURCE

Steroids 23: 155-163. February 1974.

ABSTRACT

To aid contraceptive research employing radioimmunoassay of steroids, a new technique for identifying mestranol

and ethinyl estradiol with high specific activity is described. Radioactive mestranol was prepared from estrone-6,7-

tritiated by methylation followed by ethinylation and purification by TLC. Radioactive ethinyl estradiol was prepared

directly from the estrons by ethinylation, removing the untreated estrone by Girard's reagent T and purifying the

product by TLC. Purity of both compounds was rechecked by the isotopic dilution technique. High specific activity

was achieved with this method as calculated by determining the loss of tritium during each step of the reaction with

a double isotope method. (PubHealth.info Document ID: CONT7T 3506-06)

PubHealth.info NOTE: The author(s) of this article titled, "Radioimmunoassay of contraceptive steroids. 2. Synthesis

of 6,7-tritiated-mestranol and ethinylestradiol of high specific activity.", is(are) Kundu N. The source of this article is

"Steroids 23: 155-163. February 1974.". This article was published in 1974 in English language(s). (PubHealth.info®

Document ID: CONT7T 3506-06. All rights reserved with PubHealth.info) PIN: 33506

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