Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1977

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Liver neoplasms and oral contraceptives.

AUTHORS

KEIFER WS J; SCOTT JC

SOURCE

AMerican Journal of Obstetrics and Gynecology 128(4): 448-454. June 15, 1977.

ABSTRACT

Until the past decade, hepatic cell adenomas had been considered rare. Since 1970 there have been 138 cases

reported in the English literature. The records of 5 major Seattle hospitals were reviewed. There were 9 cases of

these tumors during this period. The patients were between the ages of 15-50. Of these, 6 had used oral

contraceptives and 3 had not. An unusual case report of a 28-year-old woman (para 1-0-0-1) complaining of infertility

and absence of menses for 6 months is presented. She had used a preparation of mestranol and ethynodiol

diacetate for 11 months. Then she had promptly conceived and had a normal delivery. After delivery she had used

the same durg intermittently for 10 months. A sensation of fullness and pressure in the right upper abdomen had

been noted. On examiantion a mass in the right side of the abdomen was detected. A liver scan showed a large

mass in the abdomen. At laparotomy a large vascular tumor mass arising from the undersurface of the liver was

excised along with the gallbladder to which it was adherent. Ovarian biopsies showed normal tissue. 30 days after

the operation the patient had her 1st spontaneous menstrual period in over 2 years. Pregnancy followed promptly and

a healthy infant was delivered by Caesarean section. Liver exploration at this time revealed no tumor masses. In the

reported cases the duration of exposure to oral contraceptives has varied from 3 to 132 months and 4 to 72 months

in the Seattle cases. Of 96 patients operated on, 12 have died of complications. A history and physical examination

have proved to be the best means of diagnosis. Radiographic evidence contributed in 68%. Liver scans and

arteriograms were useful when used. In 2 instances pregnancy was present when hepatic rupture occurred and 6

were recently postpartum. In 10 of the reported cases there was an interval of 6 months to 10 years between

ingestion of ovulation inhibitors and appearance of tumors. In an accompanying discussion it is emphasized that

mestranol was the drug most frequently associated with these tumors. (PubHealth.info Document ID: CONT7T 31-06)

PubHealth.info NOTE: The author(s) of this article titled, "Liver neoplasms and oral contraceptives.", is(are) KEIFER

WS J; SCOTT JC. The source of this article is "AMerican Journal of Obstetrics and Gynecology 128(4): 448-454.

June 15, 1977.". This article was published in 1977 in English language(s). (PubHealth.info® Document ID:

CONT7T 31-06. All rights reserved with PubHealth.info) PIN: 30031

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