Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1975

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Potentiation of hypothalamic pressor responses in awake rats pretreated with

contraceptive steroids.

AUTHORS

Bunag RD; Mueting N; Eferakeya A

SOURCE

Pharmacology 13: 27-39. 1975.

ABSTRACT

Experimental results of the potentiation of hypothalamic pressor responses in awake female rats pretreated with

contraceptive steroids are presented. 2 groups of rats (30 in each group) which differed only in age (3 and 10 weeks

old) received corn oil, mestranol, norethynodrel, Enovid, Enovid plus saline, or desoxycorticosterone acetate (DOCA)

for 20 weeks. Body weights and blood pressures were measured regularly. Following the 20 weeks, acute

experiments involving hypothalamic stimulation and injection of pressor agents were performed. After DOCA

implantation mature rate developed hypertension. Enovid-treated rats (5 weeks old at onset of treatment) had higher

pressures (p less than .05) than those given corn oil during Weeks 8, 10, 13, and 19 only. Mature rats given Enovid

had only slight and occasional increases in blood pressure. When Enovid treatment was initiated at 3 weeks of age,

pressure elevations remained infrequent and transient. After 20 weeks of pretreatment pressor responses to

norepinephrine or angiotensin were unaffected; however those to electrical stimulation of the posterior hypothalamus

were increased in rats pretreated with Enovid. These results were explained by an increased sensitivity of

hypothalamic pressor areas produced by Enovid prior to the development of hypertension. (PubHealth.info Document

ID: CONT7T 3089-06)

PubHealth.info NOTE: The author(s) of this article titled, "Potentiation of hypothalamic pressor responses in awake

rats pretreated with contraceptive steroids.", is(are) Bunag RD; Mueting N; Eferakeya A. The source of this article is

"Pharmacology 13: 27-39. 1975.". This article was published in 1975 in English language(s). (PubHealth.info®

Document ID: CONT7T 3089-06. All rights reserved with PubHealth.info) PIN: 33089

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