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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1983




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Oral contraception with a new biphasic preparation. [Orale Kontrazeption

mit neuem Zweiphasenpraparat.]



AUTHORS

Balmer J


SOURCE

Ars Medici. 1983;73(5):226-8.



ABSTRACT

In an open multicenter study, in which 50 gynecologists took part, a biphasic combination contraceptive was tested

in 440 women (2164 documented cycles). Binovum is a 21-day regimen containing ethinyl estradiol (EE) and

norethindrone (NE); the 1st 10 tablets contain 0.035 mg EE and 0.5 mg NE, the other 11 tablets contain 0.035 mg EE

and 1.0 mg NE. All women (age range 15-47 years) were tested for at least 6 cycles. Body weight remained within

normal physiological range througout the study. 60% registered 6 uninterrupted cycles. Spotting and/or breakthrough

bleeding decreased from 26.1% in the 1st cycle to 8% in the 2nd cycle; only 4.2% of the subjects registered spotting

after 6 cycles, 3.8% had breakthrough bleeding; i.e., 92% of all women had normal cycles. Average spotting rate was

8.2%, breakthrough rate 8.1%. Withdrawal bleeding was 7% after 3 cycles, 3% after 6 cycles (average 6%). Side

effects such as breast tenderness, nausea, headache decreased from 21.8% (1st cycle) to 6.4% (6th cycle).

Tolerance was good to very good in 86.6%. 61.3% of the women were first-time pill users; others switched from one

agent to Binovum without pause. compares favorably with a triphasic preparation and with another combination

contraceptive containing a new kind of Progestin used in swedish studies. Side effects decrease with longer use.

NE has only a negligible effect on the endometrium (no postpill amenorrhea), has a favorable effect on acne, and has

no effect on HDL levels. All this points to the suitability of Binovum for initial adjustment to the pill or a changeover

from other agents. (PubHealth.info Document ID: CONT5T 2063-06)



PubHealth.info NOTE: The author(s) of this article titled, "Oral contraception with a new biphasic preparation. [Orale

Kontrazeption mit neuem Zweiphasenpraparat.]", is(are) Balmer J. The source of this article is "Ars Medici.

1983;73(5):226-8.". This article was published in 1983 in German language(s). (PubHealth.info® Document ID:

CONT5T 2063-06. All rights reserved with PubHealth.info) PIN: 22063





 

 

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