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PubHealth.info®
(a subsidiary of
PakMed) presents scientific information mainly
based on abstracts of articles published on a variety of public health issues/topics,
particularly encompassing
population planning, disease prevention, maternal and child health,
and communicable and
non-communicable diseases (like HIV AIDS, malaria, etc) that are
affecting a significant portion of population in developing and
developed
countries. Here you can find abstracts of articles published on a variety of public health
topics under category "Contraception
(Birth Control) and Family Planning".
Contraception (birth control)
is a regimen of one or more actions, devices, or medications followed in
order to deliberately prevent or reduce the likelihood of a woman
becoming pregnant or giving birth. Therefore contraception is the
utilization of various and sundry surgical procedures, devices,
practices, agents, or drugs with the intention of preventing conception
or impregnation (pregnancy). Methods and intentions typically termed
birth control may be considered a pivotal ingredient to family
planning. Birth control is a controversial political and ethical
issue in many cultures and religions, and although it is generally less
controversial than abortion specifically. |
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| CATEGORY: |
Contraception (Birth Control) and Family Planning |
| Hormonal contraceptives: does one dose fit all? |
| OUTLOOK. 1991 Apr;9(1):7-8. |
| Pharmacokinetic research demonstrates that hormonal contraceptives are metabolized differently depending on the |
| individuals and even within the same individual over time. For example, pooled data from international studies reveal |
| that, among users of NORPLANT, the heavier women (>70 kg) had a higher failure rate (as high as 8.5%) than lighter |
| women (<50 kg; .2%). Another study's results show lower average plasma levels of ethinyl estradiol in women taking |
| 50 mcg of ethinyl estradiol from Nigeria, Singapore, and Sri Lanka than those from the US and Thailand, even after |
| adjustment for body size. Multicenter trial data of the experimental testosterone enanthate injectable contraceptive |
| demonstrates that 91% of the men in the Chinese centers had azoospermia whereas only 60% of those at other |
| centers had it. Body size did not account for this difference. Results from a pharmacokinetic study in the US of |
| women taking a combined oral contraceptive (.25 mg levonorgestrel and 50 mcg ethinyl estradiol) over 3 months |
| reveals that significant differences existed in each woman's serum hormone levels immediately after each dose. |
| Researchers wonder if these variances are due to diet, health status, stature, and ethnicity. Some are contemplating |
| the feasibility and practicality of actually adjusting hormonal methods for specific groups to optimize safety and |
| efficacy. In areas where logistics capabilities are limited and/or are limited resources for family planning programs, |
| adjusting hormonal methods is neither practical nor feasible. Moreover variability does occur within each person. |
| More pharmacokinetic research is needed so the scientific community can learn what factors influence the variability |
| in steroid metabolism and whether this variability substantially affects method effectiveness, safety, and |
| acceptability. (PubHealth.info Document ID: CONT3T 2049-06) |
| PubHealth.info NOTE: The author(s) of this article titled, "Hormonal contraceptives: does one dose fit all?", is(are) . |
| The source of this article is "OUTLOOK. 1991 Apr;9(1):7-8.". This article was published in 1991 in English |
| language(s). (PubHealth.info® Document ID: CONT3T 2049-06. All rights reserved with PubHealth.info) PIN: 12049 |
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