Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1991

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Hepatocellular carcinoma coexisting with hepatic adenoma. Incidental

discovery after long-term oral contraceptive use.

AUTHORS

Korula J; Yellin A; Kanel G; Campofiori G; Nichols P

SOURCE

WESTERN JOURNAL OF MEDICINE. 1991 Oct;155(4):416-8.

ABSTRACT

In March 1989, ultrasonography revealed a hepatic mass in a 40 year old nulliparous woman who was then referred to

the University of Southern California--Los Angeles (UCLA) Liver Unit. She exhibited no symptoms of a liver

condition. From 19-28 years old, she took the combined oral contraceptive (OC) Ovulen 21 for irregular menses. After

a brief period of taking Ortho Novum 1/80, she took Demulen 1/35-24 between ages 28-34. Her physician diagnoses

endometriosis at 34. He stopped OC therapy and prescribed the progestin Norlutate. She had no history of hepatitis,

toxin exposure, and previous liver disease. Further no one in her family had had liver disease or neoplasms.

Computer tomography identified a 6.5 cm x 3.5 cm mass in the right lobe of the liver which matched a cold defect on

a liver scan using technetium Tc 99m sulfur colloid. The mass selectively took up gallium. Arteriography revealed

the mass to be a vascular tumor, but it did not exhibit a typical vascular pattern of an adenoma or the neovascularity

of hepatocellular carcinoma. Physicians at UCLA used peritoneoscopy to take percutaneous needle biopsies of the

right lobe which confirmed a hepatic adenoma. they then removed the right lobe of the liver. The remaining part of

the liver was normal. Histologic examinations of the removed section showed features of a well differentiated

hepatocellular carcinoma. Further tumor cells had invaded normal hepatic parenchyma. The physicians believed

that hepatic adenoma was in the process of transforming into hepatocellular carcinoma in this patient. They thought

that long term OC use, and possibly long term progestin use, may have contributed to the formation of the liver

neoplasms. They emphasized the need for a pilot study to develop guidelines on surveillance ultrasonography of

women taking OCs over a long period. (PubHealth.info Document ID: CONT3T 2042-06)

PubHealth.info NOTE: The author(s) of this article titled, "Hepatocellular carcinoma coexisting with hepatic

adenoma. Incidental discovery after long-term oral contraceptive use.", is(are) Korula J; Yellin A; Kanel G;

Campofiori G; Nichols P. The source of this article is "WESTERN JOURNAL OF MEDICINE. 1991 Oct;155(4):416-

8.". This article was published in 1991 in English language(s). (PubHealth.info® Document ID: CONT3T 2042-06. All

rights reserved with PubHealth.info) PIN: 12042

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