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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1991




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



In utero exposure to steroid contraceptives and outcome of pregnancy.



AUTHORS

Pardthaisong T; Gray RH


SOURCE

AMERICAN JOURNAL OF EPIDEMIOLOGY. 1991 Oct 15;134(8):795-803.



ABSTRACT

A cohort study of women who used steroid contraceptives during pregnancy was conducted in Chiang Mai, northern

Thailand, between 1984-1987. There were 1573 pregnancies in which the fetus was exposed to the injectable

contraceptive Depo-Provera (Upjohn Company, Kalamazoo, Michigan). 830 accidental pregnancies and 743 infants

conceived before the mother began using Depo-Provera were noted, 601 accidental pregnancies occurred in women

who used oral contraceptives (OCs), and 2578 planned pregnancies occurred with no steroid exposures (controls).

Subjects were followed for interview, and medical records were traced for birthweight. Women using Depo-Provera

had more risk factors for adverse pregnancy outcomes than did the other groups. The adjusted odds ratios (OR) for

low birthweight were increased for accidental pregnancies with fetal exposure to Depo-Provera (OR=1.5, 95%

confidence interval [CI] 1.2-1.9) or OCs (OR=1.5, 05% CI 1.2-2.0). The higher risk of low birthweight among infants

exposed in utero to Depo-Provera or OCs is due in part to self-selection for adverse outcomes among women with

unplanned pregnancies. However, among accidental pregnancies with Depo-Provera, the risk of low birthweight was

significantly increased when conception was estimated to have occurred within 4 weeks of injection. The ORs were

1.9 (95% CI 1.4-3.2) for injection-to-conception intervals of <or= 4 weeks, 1.5 (95% CI 0.9-2.3) for intervals of 5-8

weeks, and 1.2 (95% CI 0.7-1.9) for intervals of >or= 9 weeks. This trend was highly significant. The authors thus

conclude that early, high-dose in utero exposures to Depo-Provera may affect fetal growth. (author's) (PubHealth.info

Document ID: CONT3T 2031-06)



PubHealth.info NOTE: The author(s) of this article titled, "In utero exposure to steroid contraceptives and outcome of

pregnancy.", is(are) Pardthaisong T; Gray RH. The source of this article is "AMERICAN JOURNAL OF

EPIDEMIOLOGY. 1991 Oct 15;134(8):795-803.". This article was published in 1991 in English language(s).

(PubHealth.info® Document ID: CONT3T 2031-06. All rights reserved with PubHealth.info) PIN: 12031


This article is peer-reviewed.




 

 

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