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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1991




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Time course of inhibition of caffeine elimination in response to the oral

depot contraceptive agent, Deposiston. Hormonal contraceptives and caffeine

elimination. [Zeitverlauf der Hemmung der Coffeinelimination unter dem

Einfluss des oralen Depotkontrazeptivum Deposiston. Hormonale Kontrazeptiva

und Coffeinelimination.]



AUTHORS

Meyer FP; Canzler E; Giers H; Walther H


SOURCE

ZENTRALBLATT FUR GYNAKOLOGIE. 1991;113(6):297-302.



ABSTRACT

Over 6 months, the influence of the oral depot contraceptive Deposiston (3 mg ethinyl estradiol sulphonate + 10 mg

norethisterone acetate/menstrual cycle) on the pharmacokinetics of caffeine as a model substance was studied in 7

women. The 1st examination began prior to the administration of the drug. The women were subjected to little

challenge as saliva was used as the basis of measurement. Deposiston was found to markedly delay the

elimination 1/2-life of caffeine (p<0.05): t 1/2 prior to therapy 4.9 +or- 2.6 hours and, after as little as 2 mg ethinyl

estradiol sulphonate, 8.0 +or- 3.5 hours. In contrast to the effect observed for preparations containing less estrogen,

these longer 1/2-lives persisted through the trial. As expected, the AUC values were slightly elevated during this

period, whereas clearance values were reduced. (summaries in GER, ENG) (PubHealth.info Document ID: CONT3T

2027-06)



PubHealth.info NOTE: The author(s) of this article titled, "Time course of inhibition of caffeine elimination in

response to the oral depot contraceptive agent, Deposiston. Hormonal contraceptives and caffeine elimination.

[Zeitverlauf der Hemmung der Coffeinelimination unter dem Einfluss des oralen Depotkontrazeptivum Deposiston.

Hormonale Kontrazeptiva und Coffeinelimination.]", is(are) Meyer FP; Canzler E; Giers H; Walther H. The source of

this article is "ZENTRALBLATT FUR GYNAKOLOGIE. 1991;113(6):297-302.". This article was published in 1991 in

German language(s). (PubHealth.info® Document ID: CONT3T 2027-06. All rights reserved with PubHealth.info) PIN:

12027

This article is peer-reviewed.




 

 

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