Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1991

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

The role of contraception in the development of postmolar gestational

trophoblastic tumor.

AUTHORS

Deicas RE; Miller DS; Rademaker AW; Lurain JR

SOURCE

OBSTETRICS AND GYNECOLOGY. 1991 Aug;78(2):221-6.

ABSTRACT

Between January 1974-June 1988, 299 evaluable patients were referred to the John I. Brewer Trophoblastic Disease

Center of Northwestern University Cancer Center for treatment and/or followup of a hydatidiform mole (n=162) or

postmolar gestational trophoblastic tumor (n=137). The type of contraception and other prognostic factors before and

after evacuation were correlated with the development of gestational trophoblastic tumor using both univariate and

multivariate analysis. There was no relationship between prehydatidiform mole contraception and the development

of gestational trophoblastic tumor. Oral contraceptives (OCs) were used by 139 patients (46%), barrier methods by

141 patients (47%), IUDs by 2 patients (1%), and no contraception by 17 patients (6%). The risk of developing

gestational trophoblastic tumor was compared between patients who used vs. those who did not use: OCs--33% vs.

57% (p<.001); barrier methods--53% vs. 40% (p=.30); IUD--100 vs. 46% )p=.21); and any contraceptive method--43%

vs. 88% (p<.001). The dose of estrogens could be determined in 75 patients taking OCs; 14 of 49 (29%) of the

patients taking less than 50 mcg vs. 9 of 26 (35%) taking 50 mcg or more developed gestational trophoblastic tumor

(p=.78). Stepwise logistic regression analysis demonstrated that the type of contraceptive used was the most

important prognostic factor in gestational trophoblastic tumor development (p<.0001), followed by the occurrence of

theca-lutein cysts (p<.0001), Asian maternal race (p=.02), less time from the last menstrual period =.005), and greater

maternal age (p=.04). There appears to be an outcome advantage for patients using OCs for contraception after

evacuation of hydatidiform mole. (author's) (PubHealth.info Document ID: CONT3T 2020-06)

PubHealth.info NOTE: The author(s) of this article titled, "The role of contraception in the development of postmolar

gestational trophoblastic tumor.", is(are) Deicas RE; Miller DS; Rademaker AW; Lurain JR. The source of this

article is "OBSTETRICS AND GYNECOLOGY. 1991 Aug;78(2):221-6.". This article was published in 1991 in English

language(s). (PubHealth.info® Document ID: CONT3T 2020-06. All rights reserved with PubHealth.info) PIN: 12020

This article is peer-reviewed.

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