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PubHealth.info®
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PakMed) presents scientific information mainly
based on abstracts of articles published on a variety of public health issues/topics,
particularly encompassing
population planning, disease prevention, maternal and child health,
and communicable and
non-communicable diseases (like HIV AIDS, malaria, etc) that are
affecting a significant portion of population in developing and
developed
countries. Here you can find abstracts of articles published on a variety of public health
topics under category "Contraception
(Birth Control) and Family Planning".
Contraception (birth control)
is a regimen of one or more actions, devices, or medications followed in
order to deliberately prevent or reduce the likelihood of a woman
becoming pregnant or giving birth. Therefore contraception is the
utilization of various and sundry surgical procedures, devices,
practices, agents, or drugs with the intention of preventing conception
or impregnation (pregnancy). Methods and intentions typically termed
birth control may be considered a pivotal ingredient to family
planning. Birth control is a controversial political and ethical
issue in many cultures and religions, and although it is generally less
controversial than abortion specifically. |
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| CATEGORY: |
Contraception (Birth Control) and Family Planning |
| A pilot study on the assessment of a progesterone / estradiol sustained |
| release as once-a-month-injectable contraceptive. |
| Garza-Flores J; Fatinikun T; Hernandez L; Ramos I; Cardenas M; Menjivar M |
| CONTRACEPTION. 1991 Jul;44(1):45-59. |
| A pilot study to assess the use of natural hormones in a microcrystalline sustained release system was undertaken |
| in normal menstruating women. Progesterone at a dose of 100 mg in combination with 5 mg estradiol-17beta |
| aqueous microcrystalline suspension (3 ml) of defined particle size range (100-250 mcm) were administered to 5 |
| female volunteers of reproductive age on day 5 of their normal menstrual cycles and then every 28 days consecutively |
| for the next 2 months. Peripheral venous blood samples were taken from these women 3 times/week for 60 days |
| after the 3rd injection in order to measure serum progesterone, estradiol 17-beta, LH, and FSH. The menstrual |
| bleeding patterns were closely monitored during the study period. Results obtained indicate that exogenous |
| hormone administration produces blood levels similar to those observed during the luteal phase of the menstrual |
| cycle. Follicular maturation as assessed by endogenous estradiol rise, above 150 pg/ml, occurred 29.7 days SD 6.4 |
| after the injection. Ovulation as measured by progesterone levels above 5 ng/ml was documented 34.4 days SD 4.3 |
| after the 3rd injection. The bleeding patterns were regular, although shorter initially, but these increased |
| progressively toward a normal pattern during the course of the study. The data suggest that the |
| progesterone/estradiol-17beta combination administered as an aqueous microcrystalline suspension is capable of |
| producing sustained ovulation inhibition and could be utilized in the design of a new once-a-month contraceptive. |
| (PubHealth.info Document ID: CONT3T 2012-06) |
| PubHealth.info NOTE: The author(s) of this article titled, "A pilot study on the assessment of a progesterone / |
| estradiol sustained release as once-a-month-injectable contraceptive.", is(are) Garza-Flores J; Fatinikun T; |
| Hernandez L; Ramos I; Cardenas M; Menjivar M. The source of this article is "CONTRACEPTION. 1991 |
| Jul;44(1):45-59.". This article was published in 1991 in English language(s). (PubHealth.info® Document ID: |
| CONT3T 2012-06. All rights reserved with PubHealth.info) PIN: 12012 |
| This article is peer-reviewed. |
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