Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1991

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Phase III clinical trial with a new oral contraceptive containing 150

micrograms desogestrel and 20 micrograms ethinylestradiol.

AUTHORS

Lammers P; op ten Berg M

SOURCE

Acta Obstetrica et Gynecologica Scandinavica. 1991;70(6):497-500.

ABSTRACT

Results are presented of a phase 3 international multicenter trial to study the effect of a new, low-dose oral

contraceptive (OC) containing 20 mcg ethinyl estradiol and 150 mcg desogestrel (Mercilon) with regard to efficacy,

cycle control, blood pressure, and acceptability. In total, 1684 women from 12 European countries were included in

the study. 4 pregnancies occurred, 3 of them patient failure and 1 tablet failure. The overall Pearl Index was 0.20.

The frequency of irregular bleeding was comparable to that recorded with other commonly used low-dose OCs. No

serious side effects occurred. The incidence of the most frequently reported subjective side effects, i.e., headache,

nausea, and breast tenderness, was already low after the 1st cycle of treatment and decreased to below pretreatment

levels with continued use. There was a small increase in mean body weight, which was confined essentially to

young women. The preparation did not affect the mean systolic or diastolic blood pressure. This new preparation

has thus far proven to be an effective, safe, and well-accepted ultra low-dose OC. (PubHealth.info Document ID:

CONT3T 2011-06)

PubHealth.info NOTE: The author(s) of this article titled, "Phase III clinical trial with a new oral contraceptive

containing 150 micrograms desogestrel and 20 micrograms ethinylestradiol.", is(are) Lammers P; op ten Berg M.

The source of this article is "Acta Obstetrica et Gynecologica Scandinavica. 1991;70(6):497-500.". This article was

published in 1991 in English language(s). (PubHealth.info® Document ID: CONT3T 2011-06. All rights reserved with

PubHealth.info) PIN: 12011

This article is peer-reviewed.

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