Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1991

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Oral contraceptives and metabolic risk markers for coronary heart disease.

AUTHORS

Crook D; Godsland IF; Wynn V

SOURCE

INTERNATIONAL JOURNAL OF FERTILITY. 1991;36 Suppl 1:38-46.

ABSTRACT

Disturbances in both the plasma lipid profile and in insulin handling have been implicated in the development of

coronary heart disease (CHD). Estrogens and progestins are known to affect significantly both lipid and insulin

metabolism. Since an increased incidence of myocardial infarction has been identified among users of oral

contraceptives (OCs), the metabolic effect of these drugs on risk factors for CHD is of interest. Comparison of a

range of monophasic and triphasic OCs that differ primarily in their progestin content has shown that lowering the

progestin dose and using a less androgenic steroid reduce the impact on both low-density lipoproteins and high-

density lipoproteins (HDLs). In terms of the HDL-2 subfraction, a lipoprotein class that may be of special relevance

to the development of CHD, low-dose norethindrone and desogestrel monophasic agents had the least adverse

effect. Triglyceride levels were increased by the low-dose OCs used in this study, something that may be

unavoidable consequence of current trends in OC development. However, the clinical significance of these

increased triglyceride levels is not clear. Glucose tolerance deteriorated similarly with all the formulation in this

study, although the effect on insulin concentrations was less marked with formulations containing lower doses of

progestins. It was concluded that reducing the progestin dose and changing the progestin type effectively reduce the

adverse effect of OCs on metabolic risk for CHD. Although further study is recommended, the use of OCs without

adverse effects on risk profile is indicated. (author's) (PubHealth.info Document ID: CONT3T 2001-06)

PubHealth.info NOTE: The author(s) of this article titled, "Oral contraceptives and metabolic risk markers for coronary

heart disease.", is(are) Crook D; Godsland IF; Wynn V. The source of this article is "INTERNATIONAL JOURNAL

OF FERTILITY. 1991;36 Suppl 1:38-46.". This article was published in 1991 in English language(s).

(PubHealth.info® Document ID: CONT3T 2001-06. All rights reserved with PubHealth.info) PIN: 12001

This article is peer-reviewed.

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