Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1992

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

The metabolic impact of oral contraceptives.

AUTHORS

Krauss RM; Burkman RT Jr

SOURCE

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 1992 Oct;167(4 Pt

2):1177-84.

ABSTRACT

Many preclinical and clinical studies reveal that changes in lipoprotein metabolism are a major contributing factor to

atherosclerosis. Hormones in oral contraceptive (OC) formulations strongly influence lipoprotein metabolism.

Specifically, estrogens bring about increases in plasma triglycerides which then cause a rise in the very low density

lipoprotein. They also decrease levels of the intermediate and low density lipoprotein which cause build up of

plaque on arterial walls. Estrogens also lead to rising high density lipoprotein (HDL) levels, especially the HDL2

subspecies. Increased HDL levels are associated with lower mortality rates from cardiovascular conditions in

women who have already experienced menopause and are on hormone replacement therapy. Combination OCs used

in the US increase plasma triglycerides, low density lipoprotein, and HDL3. The estrogen dose and the relative

androgenicity of the progestin together influence the changes in HDL and HDL2. Even though low dose combined

OCs bring about lipoprotein changes which are lower than those of higher dose OCs, the changes often remain

significant. The progestin component of OCs is responsible for most changes in carbohydrate metabolism.

Specifically OC use can lead to increased levels of plasma insulin, insulin resistance, and relative glucose

intolerance. A curve analysis of glucose tolerance tests reveals this intolerance effect of OCs. The changes in

carbohydrate metabolism are not as great in women using the lower dose OCs or formulations using the new

progestins, however. (PubHealth.info Document ID: CONT3T 1552-06)

PubHealth.info NOTE: The author(s) of this article titled, "The metabolic impact of oral contraceptives.", is(are)

Krauss RM; Burkman RT Jr. The source of this article is "AMERICAN JOURNAL OF OBSTETRICS AND

GYNECOLOGY. 1992 Oct;167(4 Pt 2):1177-84.". This article was published in 1992 in English language(s).

(PubHealth.info® Document ID: CONT3T 1552-06. All rights reserved with PubHealth.info) PIN: 11552

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