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PubHealth.info®
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PakMed) presents scientific information mainly
based on abstracts of articles published on a variety of public health issues/topics,
particularly encompassing
population planning, disease prevention, maternal and child health,
and communicable and
non-communicable diseases (like HIV AIDS, malaria, etc) that are
affecting a significant portion of population in developing and
developed
countries. Here you can find abstracts of articles published on a variety of public health
topics under category "Contraception
(Birth Control) and Family Planning".
Contraception (birth control)
is a regimen of one or more actions, devices, or medications followed in
order to deliberately prevent or reduce the likelihood of a woman
becoming pregnant or giving birth. Therefore contraception is the
utilization of various and sundry surgical procedures, devices,
practices, agents, or drugs with the intention of preventing conception
or impregnation (pregnancy). Methods and intentions typically termed
birth control may be considered a pivotal ingredient to family
planning. Birth control is a controversial political and ethical
issue in many cultures and religions, and although it is generally less
controversial than abortion specifically. |
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| CATEGORY: |
Contraception (Birth Control) and Family Planning |
| LHRH analogues for contraception in women. |
| CONTRACEPTION. 1992 Aug;46(2):183-8. |
| A brief summary of the status of luteinizing hormone-releasing hormone (LH-RH) analogs and antagonists as |
| contraceptive agents concludes that the analogs are well suited for postpartum contraception and the antagonists |
| may be potential postcoital agents. LH-RH analogs have been tried in both continuous and intermittent schedules, |
| but cause problems, either those of estrogen deficit in the case of continuous use or unpredictable bleeding in |
| intermittent doses. They appear ideal, however, for postpartum contraception in women who breast feed and want to |
| space pregnancy. LH-RH agonists suppress estrogen levels, but this is normal in the postpartum. They are small |
| peptides that are digested by the child's gut if they appear in breast milk. The analogs buserelin and nafarelin are |
| currently given by nasal spray, an impractical and wasteful route of administration, especially for developing areas. |
| Depot formulations, rods, disks, or microcapsules for injection are being worked out, typically polylactide-glycolide |
| copolymers, which are biodegradable to naturally occurring metabolites. 3-6 mg will suppress pituitary function for 3 |
| months. More research is needed to keep the initial release rate in physiological range. These agents are also |
| being considered for long term contraception in western women, to mimic the persistent amenorrhea that existed in |
| previous eras. LH-RH antagonists face many more problems as contraceptive agents; they have irritating side |
| effects, releasing histamine locally; require high doses, and last only 1-3 days; may be overridden by the pituitary; or |
| the dominant follicle may become resistant. Nevertheless, LH-RH antagonists are potential postcoital methods for 1 |
| time use, because they are effective briefly in both the follicular and luteal phase. Clinical trials have not yet been |
| conducted on LH-RH antagonists for postcoital agents. (PubHealth.info Document ID: CONT3T 1549-06) |
| PubHealth.info NOTE: The author(s) of this article titled, "LHRH analogues for contraception in women.", is(are) |
| Fraser HM. The source of this article is "CONTRACEPTION. 1992 Aug;46(2):183-8.". This article was published in |
| 1992 in English language(s). (PubHealth.info® Document ID: CONT3T 1549-06. All rights reserved with |
| PubHealth.info) PIN: 11549 |
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