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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1997




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Data complement anti-STD activity of PRO 2000 gel. Contraceptives.



AUTHORS


SOURCE

AIDS WEEKLY PLUS. 1997 May 19;:15.



ABSTRACT

Procept, Cambridge, Massachusetts, announced preclinical results demonstrating the contraceptive efficacy of its

PRO 2000 topical microbicide gel. In a program of late-breaking discoveries presented at the National Conference

on Women and HIV, held in Pasadena, California, Procept scientists described the results of studies recently

conducted with PRO 2000. The in vitro results showed that PRO 2000 was contraceptive when rabbits were dosed

intravaginally with a gel containing a 4% concentration of PRO 2000. At a concentration about 10 times lower, PRO

2000 did not appear to affect the rabbit pregnancy rate. Results of preclinical tests have indicated that both

concentrations prevent HIV infection, suggesting that contraceptive and noncontraceptive formulations of this drug

may be developed. "The potential of this compound as an advancement in the area of women's health is significant,"

said Stanley C. Erck, Procept. "We believe that the contraceptive properties demonstrated by PRO 2000 Gel will

complement the anti-HIV/STD activity we will be evaluating in clinical trials." "More than 70% of all HIV infections

worldwide follow heterosexual intercourse. A major problem confounding efforts to prevent AIDS in women has been

the lack of effective, female-controlled barrier methods. PRO 2000 Gel has been identified as a topical microbicide

well suited for use by women to prevent HIV infection. In laboratory studies, PRO 2000 blocked infection by a wide

variety of HIV strains and also was active against herpes simplex virus." Clinical studies currently are underway to

assess the safety of PRO 2000 Gel in healthy female volunteers. Assuming the results of these studies are positive,

additional studies will be conducted to demonstrate safety and efficacy in populations at high risk for HIV infection.

(PubHealth.info Document ID: CONT2T 532-06)



PubHealth.info NOTE: The author(s) of this article titled, "Data complement anti-STD activity of PRO 2000 gel.

Contraceptives.", is(are) . The source of this article is "AIDS WEEKLY PLUS. 1997 May 19;:15.". This article was

published in 1997 in English language(s). (PubHealth.info® Document ID: CONT2T 532-06. All rights reserved with

PubHealth.info) PIN: 5532





 

 

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