Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1993

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effects of Norplant contraceptive subdermal implants on serum lipids and

lipoproteins.

AUTHORS

Otubu JA; Towobola OA; Aisien AO; Ogunkeye OO

SOURCE

CONTRACEPTION. 1993 Feb;47(2):149-59.

ABSTRACT

A longitudinal, short-term study of women using NORPLANT (levonorgestrel implants) was conducted. Cholesterol

content of the major lipoproteins along with total cholesterol and triglycerides were measured in fasting blood

samples from 32 women volunteers. Results for lipids and lipoproteins determined 6 and 12 months post-

NORPLANT insertion were compared with values obtained for samples taken just before implantation. Total serum

triglycerides was significantly reduced (p<0.01) from 1.14 +or- 0.44 mmol/1 (mean +or- SD) to 0.89 +or- 0.25 mmol/1

at 6 and to 0.89 +or- 0.34 mmol/1 at 12 months postinsertion. Serum total cholesterol was 3.97 +or- 0.53 mmol/1 at

the time of insertion, while at 6 and 12 months postinsertion they were 3.65 +or- 0.49 mmol/1 and 3.56 +or- 0.71

mmol/1, respectively. These changes in values from the time of insertion to 12 months, were statistically significant

(p<0.02). As regards lipoprotein fractions, high density lipoprotein cholesterol (HDL-chol) exhibited statistically

significant reductions (p<0.001) from 1.38 +or- 0.34 mmol/1 to 0.71 +or- 0.30 mmol/1 (mean +or- SD) 6 months

postinsertion. Although the value had improved to 1.14 +or- 0.38 mmol/1 by 12 months, the value was still

significantly different from the preinsertion value. The low density lipoprotein cholesterol (LDL-chol) had a mean

value (+or- SD) of 2.08 +or- 0.45 mmol/1 at the time of insertion. This was significantly elevated (p<9.991) at 6

months to 2.54 +or- 0.48 mmol/1 (mean +or- SD). The 12 month postinsertion value of LDL-chol (2.02 +or- 0.79) was

similar to the preinsertion value. The shift in HDL-chol and LDL-chol within 6 months followed by a virtual return to

the preinsertion values may represent only a transient change in metabolism of lipids and lipoproteins consequent

upon NORPLANT contraception. (PubHealth.info Document ID: CONT2T 4547-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effects of Norplant contraceptive subdermal implants on

serum lipids and lipoproteins.", is(are) Otubu JA; Towobola OA; Aisien AO; Ogunkeye OO. The source of this

article is "CONTRACEPTION. 1993 Feb;47(2):149-59.". This article was published in 1993 in English language(s).

(PubHealth.info® Document ID: CONT2T 4547-06. All rights reserved with PubHealth.info) PIN: 9547

This article is peer-reviewed.

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