Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1993

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effect of the intrauterine contraceptive device on protein components of

human uterine fluid.

AUTHORS

Tauber PF; Cramer GM; Zaneveld LJ

SOURCE

CONTRACEPTION. 1993 Nov;48(5):494-512.

ABSTRACT

The albumin, immunoglobulin G (IgG), immunoglobulin A (IgA), lysozyme, lactoferrin, alpha1-antitrypsin, alpha1x-

antichymotrypsin, and neutral proteinase levels of uterine fluid and serum of IUD-bearing women were studied in

relationship to the phase of the menstrual cycle, the length of IUD implantation, and the presence of reported side

effects. Selection of these proteins was based on their potential importance in IUD-induced contraceptive action

and/or side effects. Generally, only small differences were found in the serum levels of these proteins during the

cycle, with different length of implantation or between patients with and without side effects. However, transudation

of proteins (albumin, IgG, alpha1-antitrypsin, alpha1x-antichymotrypsin) from blood into the uterine cavity was

enhanced by the IUD, especially during the postmenstrual and premenstrual periods. The IUD enhanced the local

secretory response even more, i.e., the increased release of proteins from the endometrium (lysozyme, neutral

proteinase, IgA) and from leukocytes (lysozyme, lactoferrin). Protein changes occurred as the period of insertion

increased. These changes in the uterine milieu may account in part for the contraceptive action of the IUD. The

secretory proteins rather than the transudation products differed between patients who showed IUD-associated side

effects vs. those who did not, implying that IUD-related pathology is primarily associated with changes in local

secretory response. The possible role of each protein in the mechanism of IUD action is presented in view of the

present findings. (PubHealth.info Document ID: CONT2T 4545-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effect of the intrauterine contraceptive device on protein

components of human uterine fluid.", is(are) Tauber PF; Cramer GM; Zaneveld LJ. The source of this article is

"CONTRACEPTION. 1993 Nov;48(5):494-512.". This article was published in 1993 in English language(s).

(PubHealth.info® Document ID: CONT2T 4545-06. All rights reserved with PubHealth.info) PIN: 9545

This article is peer-reviewed.

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