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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1993




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



A comparative study of two low-dose combined oral contraceptives: results

from a multicenter trial.



AUTHORS

Dunson TR; McLaurin VL; Israngkura B; Leelapattana B; Mukherjee R; Perez-

Palacios G; Saleh AA


SOURCE

CONTRACEPTION. 1993 Aug;48(2):109-19.



ABSTRACT

A comparative multicenter clinical trial of 2 low-dose combined oral contraceptives (OCs) was conducted in

Malaysia, Egypt, Thailand, and Mexico. Efficacy, safety, and acceptability were investigated in women taking either a

norgestrel-based (NG) OC or a norethindrone acetate-based (NA) OC. This paper includes analysis of 892 women,

all of whom are at last 42 days, but within 26 weeks, postpartum and randomly allocated to 1 of the above OCs.

Follow-up visits were scheduled at 1, 4, 8 and 12 months after admission. Baseline sociodemographic

characteristics were similar for both groups, as well as compliance. There were 9 unintended pregnancies reported;

8 of these occurring in the NA group. Adverse experiences were minor with headaches and dizziness being the most

common complaints; frequency of reports was similar in both groups. The groups taking the NG-based OC had

significantly (p < .05) fewer menstrual-related complaints. Discontinuations due to menstrual problems were

significantly more common among NA users (primarily amenorrhea). Discontinuations in the NG group were primarily

for other personal reasons, e.g. unable to return to the clinic. There was also a significant difference between the 2

groups for the 11-month gross cumulative life table discontinuation rates due to menstrual problems (p < .01); the NA

group had the higher rate. (PubHealth.info Document ID: CONT2T 4531-06)



PubHealth.info NOTE: The author(s) of this article titled, "A comparative study of two low-dose combined oral

contraceptives: results from a multicenter trial.", is(are) Dunson TR; McLaurin VL; Israngkura B; Leelapattana B;

Mukherjee R; Perez-Palacios G; Saleh AA. The source of this article is "CONTRACEPTION. 1993 Aug;48(2):109-

19.". This article was published in 1993 in English language(s). (PubHealth.info® Document ID: CONT2T 4531-06.

All rights reserved with PubHealth.info) PIN: 9531


This article is peer-reviewed.




 

 

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