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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1995




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



The role of oral contraceptives in the treatment of hyperandrogenic

disorders.



AUTHORS

Burkman RT Jr


SOURCE

AMERICAN JOURNAL OF MEDICINE. 1995 Jan 16;98(1A):130S-136S.



ABSTRACT

Hyperandrogenism effects clinical symptoms (e.g., excess body hair and acne) that concern women. Combined oral

contraceptives (OCs) can treat these bothersome manifestations as well as address the effects of unopposed

estrogen common to hyperandrogenism among otherwise healthy women. OCs may improve excess androgen

conditions by suppressing gonadotropins, especially luteinizing hormone; reducing circulating androgens, especially

free testosterone; increasing serum androgen binding to sex hormone binding globulin; suppressing, adrenal

androgen secretion; inhibiting 5 alpha-reductase; and inhibiting binding of androgen receptors. Other benefits of

OCs, particularly low-dose OCs, among hyperandrogenic women include contraception, favorable effect on lipid

metabolism, good menstrual cycle control, and reduced risk of ovarian and endometrial cancer, pelvic inflammatory

disease, dysmenorrhea, and iron deficiency anemia. Providers need to consider other androgen-related problems of

each individual patient before prescribing OCs, such as diabetes, lipid/lipoprotein abnormalities, and hypertension.

Women with anovulatory hyperandrogenic conditions (e.g., polycystic ovarian syndrome) are more likely to have a

varied response to OC use than hyperandrogenic women who ovulate. The more estrogen dependent OCs appear to

benefit women with anovulatory hyperandrogenic conditions, however. OCs reduce hair cover in 60-100% of women

with hirsutism. They significantly improve acne also. OC use may diminish the risk of developing anovulation-

related endometrial hyperplasia. Low-dose OCs with the newer progestins (e.g., norgestimate and desogestrel) either

have no effect on or benefit metabolism. (PubHealth.info Document ID: CONT2T 3092-06)



PubHealth.info NOTE: The author(s) of this article titled, "The role of oral contraceptives in the treatment of

hyperandrogenic disorders.", is(are) Burkman RT Jr. The source of this article is "AMERICAN JOURNAL OF

MEDICINE. 1995 Jan 16;98(1A):130S-136S.". This article was published in 1995 in English language(s).

(PubHealth.info® Document ID: CONT2T 3092-06. All rights reserved with PubHealth.info) PIN: 8092





 

 

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