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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1995




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Pregnancy and lifestyle study: the long-term use of the contraceptive pill

and the risk of age-related miscarriage.



AUTHORS

Ford JH; MacCormac L


SOURCE

HUMAN REPRODUCTION. 1995 Jun;10(6):1397-402.



ABSTRACT

The impact of oral contraceptive use on ovarian follicular dynamics--considered to be a key determinant of trisomic

conceptions--was investigated in a prospective study of 585 Australian women who were planning pregnancy. Urine

samples were collected on the last day of each menstrual cycle in which conception was attempted; outcomes were

classified as live birth of a normal infant, spontaneous abortion, or persisting infertility. Only 39 women had never

used oral contraceptives (OCs); the majority had used the pill for at least six months. The age-related miscarriage

rate was 13.4% in women aged 25-29 years, 17.3% in those aged 30-34 years, and 28.3% in those aged 35-39 years.

The frequency of miscarriage showed a pattern of decline with increasing years of OC use: 0-2, 22.2%; 3-4, 17.3%;

5-6, 19.6%; 7-8, 16.7%; and 9 or more, 11.4%. However, the addition of maternal age to the logistic regression model

revealed that the association between OC use duration and miscarriage was significant (p < 0.001) only for women

30 years of age and over. In this latter group. the mean miscarriage rate decreased from 28% with 0-2 years of OC

use to 7% with 9 or more years of use. It is hypothesized that the decrease of about 15% in the rate of miscarriage

among longterm pill users aged 30 years or over is attributable to OC-related preservation of ovarian follicles and a

subsequent reduction in spontaneous abortion due to aneuploidy--a defect related to pre-menopausal declines in

follicle numbers. (PubHealth.info Document ID: CONT2T 3012-06)



PubHealth.info NOTE: The author(s) of this article titled, "Pregnancy and lifestyle study: the long-term use of the

contraceptive pill and the risk of age-related miscarriage.", is(are) Ford JH; MacCormac L. The source of this article

is "HUMAN REPRODUCTION. 1995 Jun;10(6):1397-402.". This article was published in 1995 in English language(s).

(PubHealth.info® Document ID: CONT2T 3012-06. All rights reserved with PubHealth.info) PIN: 8012





 

 

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