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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1995




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



The effects of two phasic oral contraceptives on hemostasis and platelet

function.



AUTHORS

Weinges KF; Wenzel E; Hellstern P; Geurts TB; Dieben TO


SOURCE

ADVANCES IN CONTRACEPTION. 1995 Sep;11(3):227-37.



ABSTRACT

At the University of Saarland, Homburg/Saar, Germany, researchers randomly assigned 20 women to either the group

using the new combiphasic oral contraceptive (OC) containing ethinyl estradiol (EE) and desogestrel (DSG) or the

group using a triphasic OC containing EE and levonorgestrel (LNG) to compare the two OCs' effects on hemostatic

parameters and platelet function. The EE dose in both OCs was comparable. The parameters were coagulation

parameters, anticoagulation parameters, fibrinolysis parameters, and platelet function parameters. Use of both the

combiphasic DSG/EE and the triphasic LNG/EE caused a modest activation of some parameters of coagulation and

fibrinolysis pathways and may have caused inhibition of antifibrinolysis. The triphasic LNG/EE modestly impaired

anticoagulation. Some of these changes were still evident during the posttreatment cycle, but to a lesser degree.

During treatment, all mean values stayed within the normal range. Neither OC affected platelet function. The

DSG/EE OC was associated with significantly higher levels of Factor VII and of plasma antithrombin-III than the

LNG/EE OC during the treatment period. During the post-treatment cycle, it was associated with significantly higher

plasma antithrombin-III and plasminogen activity and levels of plasma antithrombin-III and of Factor X. These

findings suggest that neither the combiphasic DSG/EE nor the triphasic LNG/EE clinically affected the overall

hemostatic balance. (PubHealth.info Document ID: CONT2T 2571-06)



PubHealth.info NOTE: The author(s) of this article titled, "The effects of two phasic oral contraceptives on

hemostasis and platelet function.", is(are) Weinges KF; Wenzel E; Hellstern P; Geurts TB; Dieben TO. The

source of this article is "ADVANCES IN CONTRACEPTION. 1995 Sep;11(3):227-37.". This article was published in

1995 in English language(s). (PubHealth.info® Document ID: CONT2T 2571-06. All rights reserved with

PubHealth.info) PIN: 7571





 

 

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