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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1995

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effects of oral contraceptives on fibrinolytic response to exercise.

AUTHORS

De Paz JA; Villa JG; Vilades E; Martin-Nuno MA; Lasierra J; Gonzalez-Gallego J

SOURCE

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE. 1995;27(7):961-6.

ABSTRACT

The influence of low-dose oral contraceptives (OCs) on the different components of the fibrinolytic system was

examined before and after maximum exercise in a group of 18 moderately active women. The group of OC users

consisted of 9 women aged 21-33 years who had been using OCs for at least 6 months prior to the study. 5 women

used OCs containing 35 mcg of ethinyl estradiol (EE) and 75 mcg of levonorgestrel (LNG); 4 women used OCs

containing 30 mcg of EE and 150 mcg of LNG. The 9 controls aged 18-29 had not been on OC medication for more

than 12 months. Both groups performed a maximal effort treadmill protocol between days 20 and 24 of the menstrual

cycle. Comparison of the resting parameters revealed higher plasma fibrin degradation products (FbDP),

plasminogen, alpha2-antiplasmin and protein C concentrations, and lower plasminogen activator inhibitor (PAI)

activity in the OC group. No differences were observed in plasma concentrations of tissue plasminogen activator (t-

PA) antigen, t-PA activity, t-PA/PAI complexes, and FbDP in both groups of subjects, while PAI activity was reduced.

No significant differences were found for the change in these parameters between controls and OC users.

Postexercise PAI activity was reduced both in controls and OC users, but no significant difference was found for the

change detected between the two groups. Exercise induced no variation in either of the groups for PAI antigen,

alpha2-plasmin, plasminogen, protein C, or protein S. These data confirm that increased t-PA release is an

important mediator in exercise-induced hyperfibrinolysis and they suggest that changes in the fibrinolytic system

induced by physical exercise are not affected by OCs. (PubHealth.info Document ID: CONT2T 2569-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effects of oral contraceptives on fibrinolytic response to

exercise.", is(are) De Paz JA; Villa JG; Vilades E; Martin-Nuno MA; Lasierra J; Gonzalez-Gallego J. The source of

this article is "MEDICINE AND SCIENCE IN SPORTS AND EXERCISE. 1995;27(7):961-6.". This article was

published in 1995 in English language(s). (PubHealth.info® Document ID: CONT2T 2569-06. All rights reserved with

PubHealth.info) PIN: 7569

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