Contraception (Birth Control) and Family Planning PubHealthInfo

[PubHealth.info Homepage] [Category Homepage] [Disclaimer/Copyrights] [Feedback]

Thank you for your kind visit to PubHealth.info®, an information portal created in technical collaboration with PakMed Biomedical Solutions * * * PubHealth.info® presents hundreds of thousands of informative Web pages on a variety of public health issues / issues * * * An ultimate source of information for teachers, students and research workers who need to find information on various public health issues, like population planning, contraception, HIV AIDS, STDs, maternal and child health, communicable and non-communicable disease, etc. * * * PubHealth.info® regularly updates the repository of these hundreds of thousands of informative Web pages * * * PubHealth.info® is one of the world's largest repositories and information portals with online Web pages on public health issues particularly those pertaining to developing countries!

PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1995

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effects of long-term administration of an oral contraceptive containing

ethinylestradiol and cyproterone acetate on lipid metabolism in women with

polycystic ovary syndrome.

AUTHORS

Falsetti L; Pasinetti E

SOURCE

Acta Obstetrica et Gynecologica Scandinavica. 1995 Jan;74(1):56-60.

ABSTRACT

In Italy, endocrinologists at the University of Brescia compared the hormonal, lipid, and glucose profiles of 72 women

with polycystic ovary syndrome (PCOS) and acne using an oral contraceptive (OC) (0.035 mg ethinyl estradiol and 2

mg cyproterone acetate) with those of 39 women who did not have PCOS. They examined their profiles before and

after 12 and 36 cycles of treatment. After cycle 12, the OC reduced luteinizing hormone (LH), follicle stimulating

hormone (FSH), and all androgen levels (p < 0.01), while it increased the levels of sex hormone binding globulin

(SHBG) (p < 0.01). After 12 cycles, the levels of triglycerides, high density lipoprotein (HDL) cholesterols, apoprotein

A1, apoprotein A2, and apoprotein B increased significantly [respectively, 52%, 19% (HDL), 15% (HDL2), and 8%

(HDL3), 34%, 35%, and 11%; p < 0.05]. The lipid profile after cycle 36 was not much different than it was after cycle

12. At baseline, the PCOS women had lower levels of HDL cholesterol and apoproteins A1 and A2 than did the

controls (p < 0.05). After 36 cycles of OC treatment, PCOS women had higher levels of triglycerides, total

cholesterol, and apoprotein B than controls (p < 0.05). Between baseline and cycle 36 of OC treatment, the low

density lipoprotein (LDL) cholesterol/HDL cholesterol ratio fell from 1.99 to 1.58. The final ratio equalled that of the

controls. The higher estrogenic activity of the OC was probably responsible for the lipid and lipoprotein changes

affected by treatment. These findings show that the OC produced an anti-atherogenic lipo-apolipoprotein pattern

which corrected the metabolic effects of hyperandrogenism. (PubHealth.info Document ID: CONT2T 2568-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effects of long-term administration of an oral contraceptive

containing ethinylestradiol and cyproterone acetate on lipid metabolism in women with polycystic ovary syndrome.",

is(are) Falsetti L; Pasinetti E. The source of this article is "Acta Obstetrica et Gynecologica Scandinavica. 1995

Jan;74(1):56-60.". This article was published in 1995 in English language(s). (PubHealth.info® Document ID:

CONT2T 2568-06. All rights reserved with PubHealth.info) PIN: 7568

This page is optimized to be viewed by Java script enabled Microsoft® Internet Explorer 6 or later version, at screen resolution of 800 by 600 pixels.