Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1995

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effect of different progestagens in low oestrogen oral contraceptives on

venous thromboembolic disease. World Health Organization Collaborative Study

of Cardiovascular Disease and Steroid Hormone Contraception.

AUTHORS

Farley TM; Meirik O; Chang CL; Marmot MG; Poulter NR

SOURCE

Lancet. 1995 Dec 16;346(8990):1582-8.

ABSTRACT

Researchers analyzed data on 829 women hospitalized for venous thromboembolism (VTE) with data on 2135 age-

and hospital-matched controls and 506 community controls to compare the risk of VTE associated with current use

of low-estrogen (<35 mcg ethinyl estradiol) oral contraceptives (OCs) containing levonorgestrel with the risks

associated with current use of low-estrogen OCs containing the third generation progestogens desogestrel or

gestodene. The women were identified in 10 collaborating centers in nine countries, most of which were in

Colombia and the UK. Even though women who used a low-estrogen OC containing levonorgestrel faced a 3.5 times

greater risk of VTE than non-users, women who used low-estrogen OCs containing the third generation

progestogens faced an even greater risk of VTE (odds ratio [OR] = 9.1, when compared with non-users). When the

researchers used general practice-based controls in the Oxford region of the UK as the control group, the risks of

VTE regardless of progestogen was higher than when they used Oxford region hospital controls (e.g., desogestrel OC

users, adjusted OR = 15 vs. 7.3). Among all centers, third generation OC users, especially gestodene users, faced

a higher risk of VTE than levonorgestrel OC users (adjusted OR = 2.7; p < 0.001). The researchers could not exclude

the possibility that chance, bias, or residual confounding influenced these unexpected findings. Independent

studies are needed to confirm these findings. Research is also needed to examine the association between the new

progestogens and reduced risk of stroke and myocardial infarction. (PubHealth.info Document ID: CONT2T 2556-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effect of different progestagens in low oestrogen oral

contraceptives on venous thromboembolic disease. World Health Organization Collaborative Study of Cardiovascular

Disease and Steroid Hormone Contraception.", is(are) Farley TM; Meirik O; Chang CL; Marmot MG; Poulter NR.

The source of this article is "Lancet. 1995 Dec 16;346(8990):1582-8.". This article was published in 1995 in English

language(s). (PubHealth.info® Document ID: CONT2T 2556-06. All rights reserved with PubHealth.info) PIN: 7556

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