Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1995

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Differential effects on bone density of progestogen-only methods for

contraception in premenopausal women.

AUTHORS

Naessen T; Olsson SE; Gudmundson J

SOURCE

CONTRACEPTION. 1995 Jul;52(1):35-9.

ABSTRACT

Researchers randomly allocated 22 premenopausal women aged 20-45 to treatment with either Depo-Provera (150

mg depot-medroxyprogesterone acetate [DMPA] injected intramuscularly every 3 months) or Norplant (30-60 g

levonorgestrel/day during 1st year of use) to determine the differences in the short-term effects (at 6 months) on bone

mass and bone metabolism. The women, clients of the Family Planning Unit of the University Hospital in Uppsala,

Sweden, gave their informed consent to try either of the types of continuous progestogen contraception. The

researchers examined biochemical indices for bone metabolism. Alkaline phosphatase and osteocalcin increased

significantly in the levonorgestrel group (1.88-2.26 mckat/l [p = 0.004] and 1.22-3.05 mcg/l [p = 0.007], respectively).

DMPA increased bone turnover (serum calcium: 2.33-2.38 [p = 0.038]; urine hydroxyproline/creatinine ratio: 12.1-24)

and bone formation (serum osteocalcin: 1.2-1.61). Women treated with levonorgestrel experienced a 2.94% increase

in forearm bone mineral density (BMDprox) (p = 0.006), while women treated with DMPA experienced an insignificant

0.41% decrease in BMDprox. These changes in BMDprox corresponded with the changes in the biochemical indices

for bone metabolism. These findings reveal that treatment with levonorgestrel at standard clinical doses for

contraception increases bone density, while treatment with DMPA at standard clinical doses for contraception does

not affect bone density. (PubHealth.info Document ID: CONT2T 2539-06)

PubHealth.info NOTE: The author(s) of this article titled, "Differential effects on bone density of progestogen-only

methods for contraception in premenopausal women.", is(are) Naessen T; Olsson SE; Gudmundson J. The source

of this article is "CONTRACEPTION. 1995 Jul;52(1):35-9.". This article was published in 1995 in English

language(s). (PubHealth.info® Document ID: CONT2T 2539-06. All rights reserved with PubHealth.info) PIN: 7539

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