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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1995




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Depo-Provera in adolescents: effects of early second injection or prior oral

contraception.



AUTHORS

Harel Z; Biro FM; Kollar LM


SOURCE

JOURNAL OF ADOLESCENT HEALTH. 1995 May;16(5):379-84.



ABSTRACT

The capability of an early second injection or prior use of oral contraceptives (OCs) to improve satisfaction and long-

term continuation of Depo-Provera in adolescents was investigated in a clinical trial involving 78 females 12-20 years

of age (average, 15.9 years) recruited from a hospital-based adolescent health clinic. 36 subjects received injection

of 150 mg of Depo-Provera every three months (Group 1), 27 received the second injection after only six weeks (Group

2), and 15 switched directly from OCs to the standard Depo-Provera regimen (Group 3). There was no difference

between Groups 1 and 2 in terms of duration or frequency of menstrual bleeding; however, prior OC users experienced

a significant reduction in the duration and intensity of bleeding in the first six months of Depo-Provera use (when

estrogen was still present in the women's systems). Overall, 64% of study subjects reported less dysmenorrhea

while on Depo-Provera. A slightly greater change in body mass index was observed among girls in Group 2 than in

Groups 1 and 3; moreover, 70% of those in the early injection group reported increased appetite and weight gain

compared to 39% of those on the standard schedule. The most commonly reported side effects included initial pain

and soreness at the injection site (27%), decreased libido (56%), mood changes (31%), depression (26%), frequent

headache (25%), fatigue (24%), and increase in acne (15%); there were no significant differences by group. 17

adolescents (22%) discontinued Depo-Provera, generally after two injections and due to bleeding irregularities or

weight gain. 87% of adolescents who were prior OC users, 52% of those on the regular schedule, and 39% of those

who received an early injection stated they were very satisfied with Depo-Provera. These findings indicate that early

second Depo-Provera injection offers no advantages; use of OCs immediately prior to Depo-Provera should be further

investigated, however, given its potential to minimize bleeding problems. (PubHealth.info Document ID: CONT2T

2524-06)



PubHealth.info NOTE: The author(s) of this article titled, "Depo-Provera in adolescents: effects of early second

injection or prior oral contraception.", is(are) Harel Z; Biro FM; Kollar LM. The source of this article is "JOURNAL OF

ADOLESCENT HEALTH. 1995 May;16(5):379-84.". This article was published in 1995 in English language(s).

(PubHealth.info® Document ID: CONT2T 2524-06. All rights reserved with PubHealth.info) PIN: 7524





 

 

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