Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1996

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

The role of triphasic levonorgestrel in oral contraception: a review of

metabolic and hemostatic effects.

AUTHORS

Lachnit-Fixson U

SOURCE

GYNECOLOGICAL ENDOCRINOLOGY. 1996 Jun;10(3):207-18.

ABSTRACT

This review of studies published since 1985 on the metabolic effects of triphasic levonorgestrel in oral

contraceptives (OCs) reveals that triphasic levonorgestrel tends not to affect lipid metabolism. Specifically, it does

not significantly change the level of the lipids associated with increased vascular risk (low density lipoprotein-

cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), and lipid ratios). Overall, triphasic levonorgestrel

OCs do not affect triglycerides, while other OCs increase the level of triglycerides. They also have a lower effect on

lipid metabolism than do monophasic levonorgestrel OCs. About 50% of the studies suggest that triphasic

levonorgestrel OCs do not affect carbohydrate metabolism, while the remaining studies suggest that they cause a

significant increase in carbohydrates. Some studies found that triphasic levonorgestrel OCs impair glucose

tolerance. Studies on the effect of triphasic levonorgestrel on hemostasis are less numerous than those on lipid and

carbohydrate metabolism. Unlike all combined monophasic OCs, triphasic levonorgestrel OCs appear to have a

balanced effect on hemostasis. In fact, they stimulate both the coagulant and anti-coagulant-fibrinolytic pathways.

Many of the researchers who found statistically significant metabolic interactions found that the changes fell within

the normal clinical range and therefore did not increase the risk of cardiovascular disease. Triphasic levonorgestrel

OCs tend to have less of a metabolic effect than its monophasic counterpart and a metabolic effect similar to other

low-dose OCs. (PubHealth.info Document ID: CONT2T 2088-06)

PubHealth.info NOTE: The author(s) of this article titled, "The role of triphasic levonorgestrel in oral contraception: a

review of metabolic and hemostatic effects.", is(are) Lachnit-Fixson U. The source of this article is

"GYNECOLOGICAL ENDOCRINOLOGY. 1996 Jun;10(3):207-18.". This article was published in 1996 in English

language(s). (PubHealth.info® Document ID: CONT2T 2088-06. All rights reserved with PubHealth.info) PIN: 7088

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