Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1996

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Role of oral contraceptives in the growth of a multilobular adenoma

associated with a hepatocellular carcinoma in a young woman.

AUTHORS

Perret AG; Mosnier JF; Porcheron J; Cuilleron M; Berthoux P; Boucheron S;

Audigier JC

SOURCE

JOURNAL OF HEPATOLOGY. 1996 Dec;25(6):976-9.

ABSTRACT

The occurrence of hepatocellular neoplasms is frequently reported in young females. The role of oral contraceptives

in the development of these tumors is considered. A 14-cm tumor was diagnosed in a 24-year-old female who had

been taking the contraceptive pill for the last 3 years. Numerous blocks of this lesion were histologically and

immunohistochemically analyzed. Some fragments of the lesion were snap-frozen in order to search for sex hormonal

receptors and hepatitis B and C virus. On histological examination, the tumor was found to be a hepatocellular,

multilobular adenoma with small foci of hepatocellular carcinoma. Neither hepatitis B virus nor hepatitis C virus was

found in the serum or in the tumor. Nuclear estrogen receptors and progesterone receptors were detected by

immunohistochemical analysis in both the adenoma and the carcinoma, but only progesterone receptors were

detected by a radio-ligand binding assay in the tumor. This finding suggests that the contraceptive pill may

stimulate the growth of hepatocellular, multilobular adenomas through the binding of hormonal compounds to their

specific receptors within tumoral cells. (PubHealth.info Document ID: CONT2T 2085-06)

PubHealth.info NOTE: The author(s) of this article titled, "Role of oral contraceptives in the growth of a multilobular

adenoma associated with a hepatocellular carcinoma in a young woman.", is(are) Perret AG; Mosnier JF;

Porcheron J; Cuilleron M; Berthoux P; Boucheron S; Audigier JC. The source of this article is "JOURNAL OF

HEPATOLOGY. 1996 Dec;25(6):976-9.". This article was published in 1996 in English language(s). (PubHealth.info®

Document ID: CONT2T 2085-06. All rights reserved with PubHealth.info) PIN: 7085

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