Contraception (Birth Control) and Family Planning PubHealthInfo

[PubHealth.info Homepage] [Category Homepage] [Disclaimer/Copyrights] [Feedback]

Thank you for your kind visit to PubHealth.info®, an information portal created in technical collaboration with PakMed Biomedical Solutions * * * PubHealth.info® presents hundreds of thousands of informative Web pages on a variety of public health issues / issues * * * An ultimate source of information for teachers, students and research workers who need to find information on various public health issues, like population planning, contraception, HIV AIDS, STDs, maternal and child health, communicable and non-communicable disease, etc. * * * PubHealth.info® regularly updates the repository of these hundreds of thousands of informative Web pages * * * PubHealth.info® is one of the world's largest repositories and information portals with online Web pages on public health issues particularly those pertaining to developing countries!

PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 1997

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Prospects of zona pellucida glycoproteins as immunogens for contraceptive

vaccine.

AUTHORS

Gupta SK; Jethanandani P; Afzalpurkar A; Kaul R; Santhanam R

SOURCE

HUMAN REPRODUCTION UPDATE. 1997 Jul-Aug;3(4):311-24.

ABSTRACT

As a result of their critical role in the fertilization process, zona pellucida glycoproteins have been considered as

potential candidate antigens for immunocontraception. In several animal models, immunization of females with zona

pellucida glycoproteins blocks fertility. This effect is associated, however, with either a transient or irreversible

alteration in the cyclicity, hormonal profile, and follicular development in the ovary. To overcome these problems,

attempts are being made to delineate relevant 'B' cell epitopes on zona pellucida proteins in order to design

immunocontraceptive vaccines based on synthetic peptides devoid of oophoritogenic 'T' cell epitopes. Monoclonal

antibodies capable of inhibiting the gamete interaction are being used to delineate such regions. Sequence

information from zona pellucida glycoproteins obtained from human and non-human primates through DNA-

recombinant technology and the availability of recombinant antigens devoid of other ovarian-associated proteins are

expected to enable immunization studies of their efficacy in fertility regulation. (PubHealth.info Document ID:

CONT2T 1015-06)

PubHealth.info NOTE: The author(s) of this article titled, "Prospects of zona pellucida glycoproteins as immunogens

for contraceptive vaccine.", is(are) Gupta SK; Jethanandani P; Afzalpurkar A; Kaul R; Santhanam R. The source

of this article is "HUMAN REPRODUCTION UPDATE. 1997 Jul-Aug;3(4):311-24.". This article was published in 1997

in English language(s). (PubHealth.info® Document ID: CONT2T 1015-06. All rights reserved with PubHealth.info)

PIN: 6015

This page is optimized to be viewed by Java script enabled Microsoft® Internet Explorer 6 or later version, at screen resolution of 800 by 600 pixels.