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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 1998




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Oral contraceptives and venous thromboembolic disease: the findings from

database studies in the United Kingdom and Germany.



AUTHORS

Farmer RD; Lawrenson RA


SOURCE

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 1998 Sep;179(3 Pt

2):S78-86.



ABSTRACT

Research articles published in 1995-96 suggested that oral contraceptives (OCs) containing desogestrel or

gestodene are associated with an increased risk of venous thromboembolism. This paper presents the findings of

two more recent studies on this association, one from the UK and the other from Germany, both of which were based

on general practice computer-generated clinical databases. The median age of OC users was 26 years in the UK

study and 27 years in the German study. The crude incidence of venous thromboembolism per 10,000 woman-years

of OC exposure was 4.1 cases in the UK study and 4.2 cases in Germany. In Germany, this rate was higher among

users of second-generation OCs (4.03 cases per 10,000 woman-years) than third-generation OCs (3.95 cases per

10,000 woman-years). In the UK, the reverse pattern was found: 4.96 and 3.10 cases per 10,000 woman-years for

third- and second-generation products, respectively. Moreover, crude incidence rates were higher for the 20 mcg

estrogen-desogestrel formulation than for the OC containing desogestrel and 30 mcg of estrogen--a biologically

implausible finding. The adjusted odds ratios in the UK study did not show any significant increases in venous

thromboembolism risk for desogestrel or gestodene compared with levonorgestrel. Overall, these findings fail to

provide support for the hypothesis that the newer progestogens are more likely to cause venous thromboembolism.

(PubHealth.info Document ID: CONT2T 10-06)



PubHealth.info NOTE: The author(s) of this article titled, "Oral contraceptives and venous thromboembolic disease:

the findings from database studies in the United Kingdom and Germany.", is(are) Farmer RD; Lawrenson RA. The

source of this article is "AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 1998 Sep;179(3 Pt 2):S78-

86.". This article was published in 1998 in English language(s). (PubHealth.info® Document ID: CONT2T 10-06. All

rights reserved with PubHealth.info) PIN: 5010





 

 

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