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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 2005




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Comparison of vaginal and oral administration of emergency contraception.



AUTHORS

Mor E; Saadat P; Kives S; White E; Reid RL


SOURCE

Fertility and Sterility. 2005 Jul;84(1):40-45.



ABSTRACT

Objective: To compare the physiologic effects of vaginally and orally administered emergency contraception. Design:

Prospective, open-label, crossover study. Setting: University research center. Patient(s): Nine regularly menstruating

volunteers. Intervention(s): Five subjects received 1,000 µg of levonorgestrel with 200 µg of ethinyl E(-2)(twice the

standard Yuzpe regimen dose) vaginally, and the standard Yuzpe regimen dose orally 1 week later. Four subjects

received 1,500 µg of levenorgestrel (twice the standard Plan B regimen dose) vaginally and received the standard

Plan B dose orally 1 week later. Serum samples were obtained at baseline an at frequent intervals after each dose.

Main Outcome Measure(s): Serum gonadotropin, hepatic globulin, and androgen levels measured at baseline, at the

time of peak levonorgestrel, and 24 hours later. Result(s): Gonadotropin, hepatic globulin, and androgen levels were

suppressed to a similar degree among the four regimens, with a return to baseline levels after 24 hours.

Conclusion(s): We conclude that high doses of levonorgestrel found in emergency contraception regimens lead to a

transient direct suppression of gonadotropin, hepatic globulin, and androgen levels. This effect is similar after

vaginal and oral administration of emergency contraception. Therefore, the vaginal route of administration of

emergency contraception regimens may be as efficacious as the oral route. (PubHealth.info Document ID: CONT1T

90-06)



PubHealth.info NOTE: The author(s) of this article titled, "Comparison of vaginal and oral administration of

emergency contraception.", is(are) Mor E; Saadat P; Kives S; White E; Reid RL. The source of this article is

"Fertility and Sterility. 2005 Jul;84(1):40-45.". This article was published in 2005 in English language(s).

(PubHealth.info® Document ID: CONT1T 90-06. All rights reserved with PubHealth.info) PIN: 90


This article is peer-reviewed.




 

 

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