Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 2005

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Bone mineral density in women aged 40-49 years using depot-

medroxyprogesterone acetate, norethisterone enanthate or combined oral

contraceptives for contraception.

AUTHORS

Beksinska ME; Smit JA; Kleinschmidt I; Farley TM; Mbatha F

SOURCE

Contraception. 2005;71:170-175.

ABSTRACT

Most studies show that depot-medroxyprogesterone acetate (DMPA) has a negative effect on bone mass. There are

conflicting reports with respect to recovery of bone mass with long-term use of DMPA. No information is available on

the effect of norethisterone enanthate (NET-EN) on bone mass, and combined oral contraceptives (COCs) have not

been found to be associated with loss of bone mass. The aim of this study was to investigate bone mineral density

(BMD) in older women (40-49 years) in relation to use of DMPA, NET-EN and COCs for at least 12 months preceding

recruitment into the study. One-hundred twenty-seven users of DMPA, 102 NET-EN users and 106 COC users were

compared to 161 nonuser controls. Bone mineral density was measured at the distal radius and midshaft of the ulna

using dual X-ray absorptiometry. There was no significant difference in BMD between the four contraceptive user

groups (p=.26) with and without adjustment for age. Although a small decrease in BMD was noted in the age of 40-

49 years, this was not statistically significant (p=.7). The BMD was found to be significantly associated with body

mass index (BMI) (p=.0001) at both measurement sites, with an increase of one unit of BMI translating to an increase

of 0.0044 g/cm(2) in radius BMD. Follicle-stimulating hormone (FSH) level =25.8 mIU/mL was associated with a

decrease of 0.017 g/cm(2) in radius BMD relative to women with FSH <25.8 mIU/mL. Significant interaction between

FSH and BMI in their effect on BMD was observed (p=.006). This study found no evidence that long-term use of

DMPA, NET-EN and COCs affects BMD in this population. (PubHealth.info Document ID: CONT1T 76-06)

PubHealth.info NOTE: The author(s) of this article titled, "Bone mineral density in women aged 40-49 years using

depot-medroxyprogesterone acetate, norethisterone enanthate or combined oral contraceptives for contraception.",

is(are) Beksinska ME; Smit JA; Kleinschmidt I; Farley TM; Mbatha F. The source of this article is "Contraception.

2005;71:170-175.". This article was published in 2005 in English language(s). (PubHealth.info® Document ID:

CONT1T 76-06. All rights reserved with PubHealth.info) PIN: 76

This article is peer-reviewed.

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