Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 2005

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Androgenic progestins in oral contraceptives and the risk of epithelial

ovarian cancer.

AUTHORS

Greer JB; Modugno F; Allen GO; Ness RB

SOURCE

Obstetrics and Gynecology. 2005 Apr;105(4):731-740.

ABSTRACT

Oral contraceptives (OCs) have been consistently linked to reduced risk of ovarian cancer. Oral contraceptive

formulations display varying degrees of androgenicity. Data linking androgens to ovarian cancer suggest that OC

androgenicity may impact efficacy in preventing ovarian cancer. The authors investigated whether OC efficacy might

differ according to androgenicity by using data from a large, population-based, case-control study (the Steroid

Hormones and Reproductions {SHARE} Study). Detailed data on OC formulation was obtained by an in-person

interview for 568 cases and 1,026 controls. Multivariable logistic regression was used to assess the association of

OC androgenicity with ovarian cancer while controlling for the known potential confounders of age, parity, family

history of ovarian cancer, and tubal ligation. Androgenic and nonandrogenic OCs conferred a similar and significant

reduction in ovarian cancer risk (odds ratio 0.52, 95% confidence interval 0.35- 0.76 and odds ratio 0.59, 95%

confidence interval 0.45- 0.78, respectively). No differences in duration of use, age at first use, and time since last

use were found between androgenic and nonandrogenic formulations. In general, the androgenicity of an OC does

not alter chemopreventive efficacy. (PubHealth.info Document ID: CONT1T 63-06)

PubHealth.info NOTE: The author(s) of this article titled, "Androgenic progestins in oral contraceptives and the risk of

epithelial ovarian cancer.", is(are) Greer JB; Modugno F; Allen GO; Ness RB. The source of this article is

"Obstetrics and Gynecology. 2005 Apr;105(4):731-740.". This article was published in 2005 in English language(s).

(PubHealth.info® Document ID: CONT1T 63-06. All rights reserved with PubHealth.info) PIN: 63

This article is peer-reviewed.

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