Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 2004

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Manipulation of the pill-free interval in oral contraceptive pill users: the

effect on follicular suppression.

AUTHORS

Schlaff WD; Lynch AM; Hughes HD; Cedars MI; Smith DL

SOURCE

American Journal of Obstetrics and Gynecology. 2004 Apr;190(4):943-951.

ABSTRACT

The purpose of this study was to compare follicular suppression that was produced by 3 different oral contraceptive

regimens that differ by treatment in the pill-free interval. In a university setting, 54 women were assigned randomly to

receive either 20 µg ethinyl estradiolC100 mg levonorgestrel followed by 7 pill-free days, 20 µg ethinyl estradiol + 150

µg desogestrel followed by 2 days of placebo then 10 µg ethinyl estradiol for 5 days, or 28 days of 20 µg ethinyl

estradiol plus 150 µg desogestrel. Follicular suppression was evaluated by serial ultrasound scans and by serum

and urinary hormone levels during a 2-month study period. Data were analyzed by nonparametric statistical tests.

There was a significant difference in follicle count among the 3 groups (P=.005). Women who were treated with a 7-

day pill-free interval experienced the least suppression. Estrogen levels were more variable and led to an observation

that overweight (body mass index, >25 kg/m²) was associated with reduced follicle suppression (relative risk, 1.6;

95% CI, 1.0, 2.7) and higher estrogen levels (relative risk, 5.3; 95% CI, 1.3, 21). Contraceptive pill users who were

treated with a 7-day pill-free interval demonstrated less follicular suppression than women who were supplemented

with either estrogen alone or estrogen plus progestin. Overweight women were less suppressed than women of

normal weight. (PubHealth.info Document ID: CONT1T 583-06)

PubHealth.info NOTE: The author(s) of this article titled, "Manipulation of the pill-free interval in oral contraceptive pill

users: the effect on follicular suppression.", is(are) Schlaff WD; Lynch AM; Hughes HD; Cedars MI; Smith DL.

The source of this article is "American Journal of Obstetrics and Gynecology. 2004 Apr;190(4):943-951.". This article

was published in 2004 in English language(s). (PubHealth.info® Document ID: CONT1T 583-06. All rights reserved

with PubHealth.info) PIN: 583

This article is peer-reviewed.

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