Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 2004

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Low-dose mifepristone for contraception: a weekly versus planned postcoital

randomized pilot study.

AUTHORS

Godfrey EM; Mawson JT; Stanwood NL; Fielding SL; Schaff EA

SOURCE

Contraception. 2004 Jul;70(1):41-46.

ABSTRACT

In this randomized pilot study, we compared the contraceptive efficacy, safety and side effect profiles of weekly

versus planned postcoital regimens of low-dose mifepristone. Forty participants were randomized to receive

mifepristone 10 mg weekly or planned postcoitally (to be used no more frequently than once every 5 days), for 12

consecutive months. Participants were evaluated monthly to determine pregnancy, ovulation status and acceptability

of physical side effects. We ended this pilot study prematurely due to low efficacy and predetermined stopping rules.

Three pregnancies during 56 woman-months occurred in the weekly group and three pregnancies during 68 woman-

months occurred in the planned postcoital group. Almost half of the participants ovulated monthly on either regimen.

The majority of the participants found the physical side effects of these regimens acceptable. Participants in the

planned postcoital group, however, found adhering to the regimen more difficult than those in the weekly group.

Mifepristone 10 mg used weekly or planned postcoitally did not adequately prevent pregnancy in our pilot study

population. Although the concept of intermittent low-dose mifepristone is appealing, the contraceptive effectiveness

was disappointing. (PubHealth.info Document ID: CONT1T 580-06)

PubHealth.info NOTE: The author(s) of this article titled, "Low-dose mifepristone for contraception: a weekly versus

planned postcoital randomized pilot study.", is(are) Godfrey EM; Mawson JT; Stanwood NL; Fielding SL; Schaff

EA. The source of this article is "Contraception. 2004 Jul;70(1):41-46.". This article was published in 2004 in

English language(s). (PubHealth.info® Document ID: CONT1T 580-06. All rights reserved with PubHealth.info) PIN:

580

This article is peer-reviewed.

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