Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 2004

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Effects of hormonal contraception on bone mineral density after 24 months of

use.

AUTHORS

Berenson AB; Breitkopf CR; Grady JJ; Rickert VI; Thomas A

SOURCE

Obstetrics and Gynecology. 2004 May;103(5 Pt 1):899-906.

ABSTRACT

The objective was to measure the effect of 24 months of depot medroxyprogesterone acetate use on bone mineral

density compared with oral contraception (pills) and nonhormonal contraception. Women aged 18-33 years self-

selected oral contraception, depot medroxyprogesterone acetate, or nonhormonal contraception (controls). Those

selecting pills were randomized to formulations containing either 35 µg ethinyl estradiol and norethindrone or 30 µg

ethinyl estradiol and desogestrel. Controls were frequency matched on age and race/ethnicity to hormonal

contraception users. Dual-energy X-ray absorptiometry of the lumbar spine (L1-L4) was performed at baseline, 12

months, and 24 months. Percent change in bone mineral density was analyzed by using analysis of covariance,

adjusting for age, race/ethnicity, weightbearing exercise, calcium intake, smoking status, and body mass index. Of

the 191 women making up the final sample, 86 used pills, 47 used depot medroxyprogesterone acetate, and 58 used

nonhormonal contraception. Women using depot medroxyprogesterone acetate for 24 months experienced, on

average, a 5.7% loss in bone mineral density, with a 3.2% loss occurring between months 12 and 24. On average,

users of desogestrel pills experienced a 2.6% loss in bone mineral density after 24 months. Bonferroni-adjusted

pairwise comparisons demonstrated that bone mineral density changes from baseline to 24 months among depot

medroxyprogesterone acetate users differed significantly from changes experienced by either of the pill groups or the

control group. Changes in bone mineral density among users of either pill did not significantly differ from each other

or from controls. Loss of bone mineral density associated with depot medroxyprogesterone acetate use appears to be

linear during the first 2 years of use. Shifts in bone mineral density among pill users were not significant when

compared with controls. (PubHealth.info Document ID: CONT1T 537-06)

PubHealth.info NOTE: The author(s) of this article titled, "Effects of hormonal contraception on bone mineral density

after 24 months of use.", is(are) Berenson AB; Breitkopf CR; Grady JJ; Rickert VI; Thomas A. The source of this

article is "Obstetrics and Gynecology. 2004 May;103(5 Pt 1):899-906.". This article was published in 2004 in English

language(s). (PubHealth.info® Document ID: CONT1T 537-06. All rights reserved with PubHealth.info) PIN: 537

This article is peer-reviewed.

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