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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.





YEAR: 2004




CATEGORY: Contraception (Birth Control) and Family Planning



TITLE



Depot medroxyprogesterone acetate, oral contraceptives and bone mineral

density in a cohort of adolescent girls.



AUTHORS

Cromer BA; Stager M; Bonny A; Lazebnik R; Rome E


SOURCE

Journal of Adolescent Health. 2004;35:434-441.



ABSTRACT

Purpose: To conduct a longitudinal comparison of bone mineral density (BMD) in 370 adolescent girls, aged 12-18,

who self-selected depot medroxyprogesterone acetate (DMPA) or an oral contraceptive (OC) containing 20µg ethinyl

estradiol/100µg levonorgestrel with that in girls who received no hormonal treatment (control group). Methods: Lumbar

spine and femoral neck BMD measurements were obtained by dual energy x-ray absorptiometry at baseline and 12

months. Data were analyzed with repeated measures analysis of covariance methods. Results: Over 12 months,

lumbar spine BMD decreased in the DMPA group (n = 29), with a mean percent change of -1.4% (95% confidence

interval [CI] - 2.73, -0.10), and increased by a mean of 3.8% (95% CI 3.11, 4.57) in the control group [n = 107 (p <

.001)]. The increase in mean percent change in lumbar spine BMD in the OC group (n = 79), 2.3% (95% CI 1.49,

3.18), was significantly smaller than in the control group (p = .03). Over 12 months, the mean percent change in

femoral neck BMD was -2.2% (95% CI -3.95, -0.39) in the DMPA group, but increased 2.3% (95% CI 1.29, 3.27) in the

control group (p < .001). The increase in mean percent change at the femoral neck in the OC group, 0.3% (95% CI -

0.87, 1.41), was significantly lower than in the control group (p = .03). Conclusions: Our study contributes to an

increasing body of knowledge indicating a negative impact of DMPA on bone health in young women. Additional

findings suggest a potential adverse effect of an OC containing 20 µg ethinyl estradiol/100 µg levonorgestrel on bone

health in adolescents. (PubHealth.info Document ID: CONT1T 522-06)



PubHealth.info NOTE: The author(s) of this article titled, "Depot medroxyprogesterone acetate, oral contraceptives

and bone mineral density in a cohort of adolescent girls.", is(are) Cromer BA; Stager M; Bonny A; Lazebnik R;

Rome E. The source of this article is "Journal of Adolescent Health. 2004;35:434-441.". This article was published

in 2004 in English language(s). (PubHealth.info® Document ID: CONT1T 522-06. All rights reserved with

PubHealth.info) PIN: 522


This article is peer-reviewed.




 

 

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