Contraception (Birth Control) and Family Planning PubHealthInfo

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PubHealth.info® (a subsidiary of PakMed) presents scientific information mainly based on abstracts of articles published on a variety of public health issues/topics, particularly encompassing population planning, disease prevention, maternal and child health, and communicable and non-communicable diseases (like HIV AIDS, malaria, etc) that are affecting a significant portion of population in developing and developed countries. Here you can find abstracts of articles published on a variety of public health topics under category "Contraception (Birth Control) and Family Planning". Contraception (birth control) is a regimen of one or more actions, devices, or medications followed in order to deliberately prevent or reduce the likelihood of a woman becoming pregnant or giving birth. Therefore contraception is the utilization of various and sundry surgical procedures, devices, practices, agents, or drugs with the intention of preventing conception or impregnation (pregnancy). Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning. Birth control is a controversial political and ethical issue in many cultures and religions, and although it is generally less controversial than abortion specifically.

YEAR: 2004

CATEGORY: Contraception (Birth Control) and Family Planning

TITLE

Contraceptive effectiveness and safety of five nonoxynol-9 spermicides: a

randomized trial.

AUTHORS

Raymond EG; Chen PL; Luoto J

SOURCE

Obstetrics and Gynecology. 2004 Mar;103(3):430-439.

ABSTRACT

To estimate and compare the effectiveness and safety of 5 spermicides over 6 and 7 months of use, respectively.

The spermicides included 3 gels containing 52.5 mg, 100 mg, and 150 mg of nonoxynol-9 per dose and a film and a

suppository, each containing 100 mg of nonoxynol-9 per dose. Women wishing to use only spermicide for

contraception for 7 months were randomly assigned to use 1 of the 5 spermicides with emergency contraception

backup. Participants were followed up for up to 30 weeks after admission. Of 1,536 women enrolled, 868 (57%) either

relied on the spermicide for 6 months or became pregnant. The probability of pregnancy during 6 months of typical

use of the spermicide was 22% (95% confidence limits 16%, 28%) in the 52.5-mg gel group, 16% (10%, 21%) in the

100-mg gel group, 14% (9%, 19%) in the 150-mg gel group, 12% (7%, 17%) in the film group, and 10% (6%, 15%) in

the suppository group. The pregnancy risk in the 52.5-mg gel group was significantly different (P < .05) from that in

either of the other gel groups. The pregnancy risks in the three 100-mg product groups were not significantly different

(P = .35). No significant differences among groups were found in the 7-month probability of specified urogenital

conditions. The gel with the lowest amount of nonoxynol- 9 was less effective than the 2 higher-dose gels. Among 3

products containing 100 mg of nonoxynol-9, formulation did not significantly affect pregnancy risk. All products were

safe. (PubHealth.info Document ID: CONT1T 507-06)

PubHealth.info NOTE: The author(s) of this article titled, "Contraceptive effectiveness and safety of five nonoxynol-9

spermicides: a randomized trial.", is(are) Raymond EG; Chen PL; Luoto J. The source of this article is "Obstetrics

and Gynecology. 2004 Mar;103(3):430-439.". This article was published in 2004 in English language(s).

(PubHealth.info® Document ID: CONT1T 507-06. All rights reserved with PubHealth.info) PIN: 507

This article is peer-reviewed.

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